Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 5/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.34 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 2/20 | 0.34 |
| ▸ | JAK3 | P52333 | 2/20 | 0.34 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22735756 | 1.00 | CCNT1 (0.35) | CCNT1CDK9TNK2RETGPR119 | |
| SCHEMBL29480761 | 0.91 | MAP3K7 (0.37) | — | |
| SCHEMBL22736348 | 0.91 | MAP3K7 (0.37) | — | |
| SCHEMBL22736147 | 0.89 | CYP3A4 (0.31) | — | |
| SCHEMBL29480757 | 0.89 | CYP3A4 (0.31) | — | |
| SCHEMBL29480733 | 0.89 | HDAC4 (0.33) | — | |
| SCHEMBL22735757 | 0.89 | HDAC4 (0.33) | — | |
| SCHEMBL29480700 | 0.85 | MELK (0.31) | — | |
| SCHEMBL22735955 | 0.81 | MAP3K7 (0.37) | — | |
| SCHEMBL29480769 | 0.81 | MAP3K7 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3976612-A1 | NOVEL COMPOUNDS FOR INHIBITION OF JANUS KINASE 1 | MANKIND PHARMA LTD (IN) | 2022-04-06 | — | — | EP | disclosed |