Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 16/20 | 0.65 |
| ▸ | FLT3 | P36888 | 13/20 | 0.65 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22551179 | 1.00 | KIT (0.65) | KITFLT3NTRK1 | |
| SCHEMBL22551167 | 0.85 | KIT (0.61) | KITFLT3 | |
| SCHEMBL29568259 | 0.85 | KIT (0.61) | KITFLT3 | |
| SCHEMBL18171380 | 0.82 | KIT (0.86) | KITFLT3 | |
| SCHEMBL24244969 | 0.82 | KIT (0.66) | KITFLT3 | |
| SCHEMBL1336328 | 0.80 | NTRK1 (0.77) | KITFLT3NTRK1 | |
| SCHEMBL24244919 | 0.80 | FLT3 (0.43) | KITFLT3NTRK1 | |
| SCHEMBL13736673 | 0.79 | KIT (1.00) | KITFLT3 | |
| SCHEMBL22551205 | 0.79 | KIT (0.54) | KITFLT3NTRK1 | |
| SCHEMBL29569157 | 0.79 | KIT (0.54) | KITFLT3NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3956315-A1 | BENZO- AND PYRIDO-PYRAZOLES AS PROTEIN KINASE INHIBITORS | Rottapharm Biotech S.r.l. (IT) | 2022-02-23 | — | — | EP | claimed |
| EP-3956315-A1 | BENZO- AND PYRIDO-PYRAZOLES AS PROTEIN KINASE INHIBITORS | Rottapharm Biotech S.r.l. (IT) | 2022-02-23 | — | — | EP | disclosed |