Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 11/20 | 0.54 |
| ▸ | FLT3 | P36888 | 8/20 | 0.54 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 3/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.42 |
| ▸ | WNT1 | P04628 | 1/20 | 0.42 |
| ▸ | CLK2 | P49760 | 1/20 | 0.42 |
| ▸ | CLK3 | P49761 | 1/20 | 0.42 |
| ▸ | INSR | P06213 | 1/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22551205 | 1.00 | KIT (0.54) | KITFLT3FGFR1KDRNTRK1 | |
| Acetic Acid SCHEMBL31561391 | 0.98 | KIT (0.54) | KITFLT3FGFR1KDRNTRK1 | |
| SCHEMBL29568745 | 0.88 | FGFR1 (0.56) | KITFLT3FGFR1KDRGSK3B | |
| SCHEMBL22551239 | 0.88 | FGFR1 (0.56) | KITFLT3FGFR1KDRGSK3B | |
| SCHEMBL29568259 | 0.85 | KIT (0.61) | KITFLT3GSK3BDYRK1A | |
| SCHEMBL22551167 | 0.85 | KIT (0.61) | KITFLT3GSK3BDYRK1A | |
| SCHEMBL22551195 | 0.84 | FGFR1 (0.57) | KITFLT3FGFR1KDRNTRK1 | |
| SCHEMBL29568040 | 0.84 | FGFR1 (0.57) | KITFLT3FGFR1KDRNTRK1 | |
| SCHEMBL22551190 | 0.82 | FGFR1 (0.43) | KITFLT3FGFR1KDRGSK3B | |
| SCHEMBL22551209 | 0.82 | FGFR1 (0.43) | KITFLT3FGFR1KDRGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3956315-B1 | BENZO- AND PYRIDO-PYRAZOLES AS PROTEIN KINASE INHIBITORS | Rottapharm Biotech Srl (IT) | 2025-04-16 | — | — | EP | claimed |
| EP-3956315-A1 | BENZO- AND PYRIDO-PYRAZOLES AS PROTEIN KINASE INHIBITORS | Rottapharm Biotech S.r.l. (IT) | 2022-02-23 | — | — | EP | claimed |
| EP-3956315-A1 | BENZO- AND PYRIDO-PYRAZOLES AS PROTEIN KINASE INHIBITORS | Rottapharm Biotech S.r.l. (IT) | 2022-02-23 | — | — | EP | disclosed |