Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 3/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.52 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | FLT3 | P36888 | 4/20 | 0.43 |
| ▸ | KDR | P35968 | 2/20 | 0.42 |
| ▸ | HTR1F | P30939 | 7/20 | 0.42 |
| ▸ | HTR1A | P08908 | 5/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29568745 | 1.00 | FGFR1 (0.56) | FGFR1HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL22551227 | 0.93 | FGFR1 (0.54) | FGFR1HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL29568591 | 0.93 | FGFR1 (0.54) | FGFR1HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL22551170 | 0.91 | FGFR1 (0.46) | FGFR1HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL29568605 | 0.91 | FGFR1 (0.46) | FGFR1HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL22551210 | 0.91 | FGFR1 (0.57) | FGFR1HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL31561379 | 0.91 | FGFR1 (0.57) | FGFR1HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL22551202 | 0.91 | FGFR1 (0.57) | FGFR1HDAC1HDAC3HDAC4HDAC7 | |
| Hydrochloric Acid SCHEMBL31561392 | 0.90 | FGFR1 (0.46) | FGFR1HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL31561378 | 0.90 | FGFR1 (0.56) | FGFR1HDAC1HDAC3HDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3956315-B1 | BENZO- AND PYRIDO-PYRAZOLES AS PROTEIN KINASE INHIBITORS | Rottapharm Biotech Srl (IT) | 2025-04-16 | — | — | EP | claimed |
| EP-3956315-A1 | BENZO- AND PYRIDO-PYRAZOLES AS PROTEIN KINASE INHIBITORS | Rottapharm Biotech S.r.l. (IT) | 2022-02-23 | — | — | EP | claimed |
| US-20220041559-A1 | BENZO-AND PYRIDO-PYRAZOLES AS PROTEIN KINASE INHIBITORS | ROTTAPHARM BIOTECH S.R.L. (IT) | 2022-02-10 | — | — | US | claimed |
| CN-114008026-A | Benzopyrazoles and pyridopyrazoles as protein kinase inhibitors | 罗达制药生物技术有限责任公司 | 2022-02-01 | — | — | CN | claimed |
| WO-2020212530-A1 | BENZO- AND PYRIDO-PYRAZOLES AS PROTEIN KINASE INHIBITORS | ROTTAPHARM BIOTECH S.R.L. (IT) | 2020-10-22 | — | — | WO | claimed |
| EP-3725777-A1 | BENZO- AND PYRIDO-PYRAZOLES AS PROTEIN KINASE INHIBITORS | Rottapharm Biotech S.r.l. (IT) | 2020-10-21 | — | — | EP | claimed |
| EP-3956315-B1 | BENZO- AND PYRIDO-PYRAZOLES AS PROTEIN KINASE INHIBITORS | Rottapharm Biotech Srl (IT) | 2025-04-16 | — | — | EP | disclosed |
| EP-3956315-A1 | BENZO- AND PYRIDO-PYRAZOLES AS PROTEIN KINASE INHIBITORS | Rottapharm Biotech S.r.l. (IT) | 2022-02-23 | — | — | EP | disclosed |
| US-20220041559-A1 | BENZO-AND PYRIDO-PYRAZOLES AS PROTEIN KINASE INHIBITORS | ROTTAPHARM BIOTECH S.R.L. (IT) | 2022-02-10 | — | — | US | disclosed |
| CN-114008026-A | Benzopyrazoles and pyridopyrazoles as protein kinase inhibitors | 罗达制药生物技术有限责任公司 | 2022-02-01 | — | — | CN | disclosed |
| WO-2020212530-A1 | BENZO- AND PYRIDO-PYRAZOLES AS PROTEIN KINASE INHIBITORS | ROTTAPHARM BIOTECH S.R.L. (IT) | 2020-10-22 | — | — | WO | disclosed |
| EP-3725777-A1 | BENZO- AND PYRIDO-PYRAZOLES AS PROTEIN KINASE INHIBITORS | Rottapharm Biotech S.r.l. (IT) | 2020-10-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220041559-A1 | BENZO-AND PYRIDO-PYRAZOLES AS PROTEIN KINASE INHIBITORS | PDXK, MAP4K2, PLK2 | FGFR1 557/4885HDAC1 503/4885HDAC3 505/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.