Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 3/20 | 0.55 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.55 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.55 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.50 |
| ▸ | SMO | Q99835 | 8/20 | 0.49 |
| ▸ | ELANE | P08246 | 1/20 | 0.48 |
| ▸ | CCNC | P24863 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | CDK8 | P49336 | 1/20 | 0.48 |
| ▸ | PASK | Q96RG2 | 1/20 | 0.48 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | VNN1 | O95497 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30006606 | 0.89 | CACNA1H (0.55) | CACNA1HCACNA1GCACNA1ITRPV1SMO | |
| SCHEMBL29269258 | 0.82 | CACNA1H (0.50) | CACNA1HCACNA1GCACNA1ITRPV1SMO | |
| SCHEMBL29430357 | 0.81 | KDM4E (0.55) | CACNA1HCACNA1GCACNA1ICCNCHTR2A | |
| SCHEMBL17316492 | 0.81 | KDM4E (0.55) | CACNA1HCACNA1GCACNA1ICCNCHTR2A | |
| SCHEMBL15491152 | 0.80 | CTNNB1 (0.51) | CACNA1HCACNA1GCACNA1ITRPV1CCNC | |
| SCHEMBL27470157 | 0.79 | CACNA1H (0.47) | CACNA1HCACNA1GCACNA1ITRPV1SMO | |
| SCHEMBL22311425 | 0.77 | CACNA1H (0.58) | CACNA1HCACNA1GCACNA1ICCNCHTR2A | |
| SCHEMBL29491495 | 0.77 | CTNNB1 (0.54) | CACNA1HCACNA1GCACNA1ICCNCHTR2A | |
| SCHEMBL1665815 | 0.77 | CTNNB1 (0.54) | CACNA1HCACNA1GCACNA1ICCNCHTR2A | |
| SCHEMBL23928858 | 0.77 | CHRNA7 (0.64) | TRPV1KDM4EALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4225745-A1 | ACETAMIDO-PHENYLBENZAMIDE DERIVATIVES AND METHODS OF USING THE SAME | Athenex, Inc. (US) | 2023-08-16 | — | — | EP | disclosed |
| WO-2022076662-A1 | ACETAMIDO-PHENYLBENZAMIDE DERIVATIVES AND METHODS OF USING THE SAME | ATHENEX, INC. (US) | 2022-04-14 | — | — | WO | disclosed |