Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 17/20 | 0.64 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31035896 | 0.85 | CHRNA7 (0.58) | CHRNA7TRPV1KDM4E | |
| SCHEMBL31035943 | 0.83 | MEN1 (0.67) | CHRNA7TRPV1KDM4EALDH1A1THRB | |
| SCHEMBL31369499 | 0.82 | CHRNA7 (0.52) | CHRNA7TRPV1KDM4EALDH1A1THRB | |
| SCHEMBL30587447 | 0.81 | CHRNA7 (0.57) | CHRNA7TRPV1KDM4E | |
| SCHEMBL23928856 | 0.81 | CHRNA7 (0.57) | CHRNA7TRPV1KDM4E | |
| SCHEMBL5094204 | 0.80 | KDM4E (0.58) | CHRNA7TRPV1KDM4EALDH1A1FAAH | |
| SCHEMBL1253366 | 0.79 | CHRNA7 (0.50) | CHRNA7TRPV1FAAH | |
| SCHEMBL6487657 | 0.77 | OXER1 (0.51) | CHRNA7TRPV1FAAH | |
| SCHEMBL29569233 | 0.77 | CACNA1H (0.55) | TRPV1KDM4EALDH1A1THRB | |
| SCHEMBL14632502 | 0.76 | ALDH2 (0.49) | CHRNA7KDM4EALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3820869-B1 | SPIROCHROMANE DERIVATIVES | RICHTER GEDEON NYRT (HU) | 2023-08-30 | — | — | EP | disclosed |
| US-20210330650-A1 | SPIROCHROMANE DERIVATIVES | RICHTER GEDEON NYRT. (HU) | 2021-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210330650-A1 | SPIROCHROMANE DERIVATIVES | CHRNA7, CHRM3, ADRB3 | CHRNA7 1/4885TRPV1 177/4885KDM4E 4415/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.