SCHEMBL29569657

SCHEMBL29569657

CC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)O

nearest known ligand 0.64

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 5/20 0.64
OPRD1 P41143 4/20 0.61
F2 P00734 1/20 0.56
NTSR1 P30989 5/20 0.55
NTSR2 O95665 4/20 0.55
SORT1 Q99523 4/20 0.55
SLC6A2 P23975 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29569996 0.91 OPRM1 (0.75) OPRM1OPRD1F2NTSR1NTSR2
SCHEMBL31114471 0.90 OPRM1 (0.63) OPRM1OPRD1NTSR1NTSR2SORT1
SCHEMBL29630683 0.90 OPRM1 (0.71) OPRM1OPRD1F2NTSR1NTSR2
SCHEMBL30273400 0.88 OPRM1 (0.64) OPRM1OPRD1F2NTSR1NTSR2
SCHEMBL29753383 0.88 OPRM1 (0.57) OPRM1OPRD1NTSR1NTSR2SORT1
SCHEMBL31370870 0.88 OPRM1 (0.63) OPRM1OPRD1NTSR1NTSR2SORT1
SCHEMBL31679387 0.87 OPRM1 (0.66) OPRM1OPRD1F2SLC6A2
SCHEMBL31114385 0.87 OPRM1 (0.57) OPRM1OPRD1NTSR1NTSR2SORT1
SCHEMBL30232040 0.87 OPRM1 (0.65) OPRM1OPRD1NTSR1NTSR2SORT1
SCHEMBL31114354 0.87 OPRM1 (0.62) OPRM1OPRD1F2NTSR1NTSR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220241377-A1 RECEPTOR-TARGETING PEPTIDE-DRUG CONJUGATES Molgenie GmbH (DE) 2022-08-04 US claimed
EP-4003403-A1 RECEPTOR-TARGETING PEPTIDE-DRUG CONJUGATES Molgenie GmbH (DE) 2022-06-01 EP claimed
CN-114450299-A Receptor-targeting peptide-drug conjugates 莫尔吉尼有限责任公司 2022-05-06 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220241377-A1 RECEPTOR-TARGETING PEPTIDE-DRUG CONJUGATES NPY1R, NPY2R, NPY5R OPRM1 300/4885OPRD1 601/4885F2 4144/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.