Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 7/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29570725 | 1.00 | KCNN4 (0.47) | KCNN4HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL29570865 | 1.00 | KCNN4 (0.47) | KCNN4HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL29571252 | 0.83 | BRD4 (0.39) | HDAC4HDAC7HDAC5 | |
| SCHEMBL24361184 | 0.82 | HDAC3 (0.41) | KCNN4HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL31322230 | 0.82 | LMNA (0.44) | KCNN4AOC3 | |
| SCHEMBL24370661 | 0.81 | KCNN4 (0.44) | KCNN4HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL24370406 | 0.81 | KCNN4 (0.44) | KCNN4HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL29570767 | 0.81 | KCNN4 (0.44) | KCNN4HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL24370405 | 0.81 | KCNN4 (0.44) | KCNN4HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL29570584 | 0.81 | KCNN4 (0.44) | KCNN4HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116802181-A | Triazolopyridine compounds as kinase inhibitors | 百时美施贵宝公司 | 2023-09-22 | — | — | CN | disclosed |
| EP-4229056-A1 | TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS | Bristol-Myers Squibb Company (US) | 2023-08-23 | — | — | EP | disclosed |
| WO-2022086828-A1 | TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2022-04-28 | — | — | WO | disclosed |