Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24325983 | 0.74 | — | — | |
| SCHEMBL24326435 | 0.72 | — | — | |
| SCHEMBL24326422 | 0.70 | ABL1 (0.31) | ACACB | |
| SCHEMBL29060385 | 0.70 | — | — | |
| SCHEMBL24326413 | 0.61 | — | — | |
| SCHEMBL27025245 | 0.60 | ACACB (0.31) | ACACB | |
| SCHEMBL24325999 | 0.60 | ACACB (0.31) | ACACB | |
| SCHEMBL24326414 | 0.58 | CTSD (0.41) | — | |
| SCHEMBL29060372 | 0.57 | — | — | |
| SCHEMBL18484467 | 0.55 | KMT2A (0.38) | ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4225447-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | Vertex Pharmaceuticals Incorporated (US) | 2023-08-16 | — | — | EP | disclosed |
| WO-2022076625-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2022-04-14 | — | — | WO | disclosed |