Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.74 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.74 |
| ▸ | TSHR | P16473 | 1/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.74 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.74 |
| ▸ | PPARG | P37231 | 1/20 | 0.58 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 6/20 | 0.56 |
| ▸ | RAB9A | P51151 | 7/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | ACKR3 | P25106 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | NSD2 | O96028 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5935612 | 1.00 | KDM4E (0.74) | KDM4EALOX15TSHRTDP1L3MBTL1 | |
| SCHEMBL28892819 | 0.87 | TDP1 (0.63) | KDM4EALOX15TSHRTDP1L3MBTL1 | |
| SCHEMBL5935587 | 0.86 | KDM4E (0.55) | KDM4EALOX15TSHRTDP1L3MBTL1 | |
| SCHEMBL6966171 | 0.84 | RAB9A (0.72) | KDM4EALOX15TSHRTDP1L3MBTL1 | |
| SCHEMBL5935621 | 0.82 | KDM4E (0.54) | KDM4EALOX15TSHRTDP1L3MBTL1 | |
| SCHEMBL5935568 | 0.82 | HPGD (0.62) | KDM4EALOX15TSHRTDP1L3MBTL1 | |
| SCHEMBL7013434 | 0.82 | HPGD (0.62) | KDM4EALOX15TSHRTDP1L3MBTL1 | |
| SCHEMBL6357256 | 0.81 | HPGD (0.61) | KDM4EALOX15TSHRTDP1L3MBTL1 | |
| SCHEMBL6357262 | 0.81 | HPGD (0.61) | KDM4EALOX15TSHRTDP1L3MBTL1 | |
| SCHEMBL5935598 | 0.81 | KMT2A (0.54) | KDM4EALOX15TSHRTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111285814-B | Quinazolinone compound containing hydrazone structural unit or stereoisomer thereof, or salt or solvate thereof | 贵州大学 | 2022-04-08 | — | — | CN | disclosed |