Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 19/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 18/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 12/20 | 0.48 |
| ▸ | HTR2C | P28335 | 4/20 | 0.46 |
| ▸ | HTR2B | P41595 | 4/20 | 0.46 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.46 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | TSPO | P30536 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23201580 | 0.85 | ADORA3 (0.47) | ADORA3ADORA1ADORA2AHTR2CHTR2B | |
| SCHEMBL15935852 | 0.85 | ADORA3 (0.47) | ADORA3ADORA1ADORA2AHTR2CHTR2B | |
| SCHEMBL29573444 | 0.85 | ADORA3 (0.47) | ADORA3ADORA1ADORA2AHTR2CHTR2B | |
| SCHEMBL12509356 | 0.85 | ADORA3 (0.47) | ADORA3ADORA1ADORA2AHTR2CHTR2B | |
| SCHEMBL29573771 | 0.83 | ADORA3 (0.61) | ADORA3ADORA1ADORA2AHTR2CHTR2B | |
| SCHEMBL29573310 | 0.82 | ADORA3 (0.54) | ADORA3ADORA1ADORA2AHTR2CHTR2B | |
| SCHEMBL29574455 | 0.82 | ADORA3 (0.55) | ADORA3ADORA1ADORA2AHTR2CHTR2B | |
| SCHEMBL29574063 | 0.82 | ADORA3 (0.73) | ADORA3ADORA1ADORA2AHTR2CHTR2B | |
| SCHEMBL29574515 | 0.77 | ADORA3 (0.40) | ADORA3ADORA1ADORA2AHTR2CHTR2B | |
| SCHEMBL12509206 | 0.76 | ADORA3 (0.40) | ADORA3ADORA1ADORA2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4196219-A1 | A3 ADENOSINE RECEPTOR AGONISTS FOR USE IN MEDICINE | Biointervene, Inc. (US) | 2023-06-21 | — | — | EP | disclosed |
| WO-2022040241-A1 | A3 ADENOSINE RECEPTOR AGONISTS FOR USE IN MEDICINE | BIOINTERVENE, INC. (US) | 2022-02-24 | — | — | WO | disclosed |