Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNPAT | O15228 | 1/20 | 0.57 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.53 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.53 |
| ▸ | MMP2 | P08253 | 6/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | ECE1 | P42892 | 1/20 | 0.49 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.48 |
| ▸ | MMP1 | P03956 | 2/20 | 0.48 |
| ▸ | MMP3 | P08254 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31170895 | 1.00 | GNPAT (0.57) | GNPATERAP2LNPEPMMP2OPRK1 | |
| SCHEMBL29596872 | 0.95 | MMP2 (0.54) | GNPATERAP2LNPEPMMP2OPRK1 | |
| SCHEMBL31181273 | 0.92 | BACE1 (0.54) | GNPATERAP2LNPEPOPRK1 | |
| SCHEMBL29612276 | 0.92 | BACE1 (0.54) | GNPATOPRK1 | |
| SCHEMBL1711598 | 0.92 | GNPAT (0.63) | GNPATERAP2LNPEPMMP2OPRK1 | |
| SCHEMBL29540649 | 0.92 | GNPAT (0.63) | GNPATERAP2LNPEPMMP2OPRK1 | |
| SCHEMBL1711765 | 0.92 | GNPAT (0.63) | GNPATERAP2LNPEPMMP2OPRK1 | |
| SCHEMBL1711769 | 0.92 | GNPAT (0.63) | GNPATERAP2LNPEPMMP2OPRK1 | |
| SCHEMBL1711591 | 0.92 | GNPAT (0.63) | GNPATERAP2LNPEPMMP2OPRK1 | |
| SCHEMBL29577411 | 0.92 | MMP2 (0.60) | GNPATERAP2LNPEPMMP2OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4367246-A2 | INTEGRIN TARGETING LIGANDS FOR OCULAR DELIVERY OF RNAI COMPOUNDS | Alnylam Pharmaceuticals, Inc. (US) | 2024-05-15 | — | — | EP | disclosed |
| WO-2023283595-A2 | INTEGRIN TARGETING LIGANDS FOR OCULAR DELIVERY OF RNAI COMPOUNDS | ALNYLAM PHARMACEUTICALS, INC. (US) | 2023-01-12 | — | — | WO | disclosed |
| WO-2022072356-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF ANGIOPOIETIN LIKE 7 (ANGPTL7) RELATED DISEASES | EMPIRICO INC. (US) | 2022-04-07 | — | — | WO | disclosed |
| EP-3976059-A2 | TREATMENT OF ANGIOPOIETIN LIKE 7 (ANGPTL7) RELATED DISEASES | EMPIRICO INC. (US) | 2022-04-06 | — | — | EP | disclosed |