⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9577861 | 0.97 | — | — | |
| Phosphoric Acid SCHEMBL18725177 | 0.88 | PLK4 (0.37) | — | |
| Sulfuric Acid SCHEMBL7493266 | 0.88 | KDM4E (0.41) | — | |
| SCHEMBL27111321 | 0.82 | PLK4 (0.35) | — | |
| SCHEMBL1770184 | 0.82 | PLK4 (0.35) | — | |
| SCHEMBL27111188 | 0.76 | PLK4 (0.33) | — | |
| SCHEMBL456591 | 0.75 | — | — | |
| SCHEMBL11878779 | 0.75 | CTH (0.31) | — | |
| SCHEMBL25838171 | 0.75 | — | — | |
| SCHEMBL11673290 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1576093-A4 | 3-DEOXYGLUCOSONE AND SKIN | DYNAMIS THERAPEUTICS INC (US) | 2009-07-08 | — | — | EP | claimed |
| US-20070065443-A1 | Fructoseamine 3 kinase and the formation of collagen and elastin | DYNAMIS THERAPEUTICS, INC. | 2007-03-22 | — | — | US | claimed |
| EP-1753861-A2 | FRUCTOSEAMINE 3 KINASE AND THE FORMATION OF COLLAGEN AND ELASTIN | Dynamis Therapeutics, Inc. (US) | 2007-02-21 | — | — | EP | claimed |
| EP-1576093-A2 | 3-DEOXYGLUCOSONE AND SKIN | Dynamis Therapeutics, Inc. (US) | 2005-09-21 | — | — | EP | claimed |
| WO-2005079463-A2 | FRUCTOSEAMINE 3 KINASE AND THE FORMATION OF COLLAGEN AND ELASTIN | DYNAMIS THERAPEUTICS, INC. (US) | 2005-09-01 | — | — | WO | claimed |
| US-20050159383-A1 | Administering enzyme inhibitors; wrinkling and aging resistance; prevents formation Advanced Glycation End Products (AGEs) | DYNAMIS THERAPEUTICS, INC. | 2005-07-21 | — | — | US | claimed |
| US-20030219440-A1 | 3-deoxyglucosone and skin | DYNAMIS THERAPEUTICS, INC. | 2003-11-27 | — | — | US | claimed |
| WO-2003089601-A2 | 3-DEOXYGLUCOSONE AND SKIN | DYNAMIS THERAPEUTICS, INC. (US) | 2003-10-30 | — | — | WO | claimed |
| WO-1992019236-A1 | 2-ALKYLIDENE-AMINOGUANIDINES FOR INHIBITING ADVANCED NONENZYMATICGLYCOSYLATION OF PROTEINS | THE ROCKEFELLER UNIVERSITY (US) | 1992-11-12 | — | — | WO | claimed |
| EP-3508516-B1 | VULCANIZED RUBBER COMPOSITION AND PRODUCTION PROCESS THEREFOR | MITSUBISHI GAS CHEMICAL CO (JP) | 2020-09-23 | — | — | EP | disclosed |
| EP-3508516-B1 | VULCANIZED RUBBER COMPOSITION AND PRODUCTION PROCESS THEREFOR | MITSUBISHI GAS CHEMICAL CO (JP) | 2020-09-23 | — | — | EP | disclosed |
| US-10369149-B2 | 4-(2-amino-tetrahydronaphthalenyl)pyrimidine derivative, preparation method therefor, and pharmaceutical composition for preventing or treating cancer, containing same as active ingredient | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2019-08-06 | — | — | US | disclosed |
| EP-3508516-A1 | VULCANIZED RUBBER COMPOSITION AND PRODUCTION PROCESS THEREFOR | Mitsubishi Gas Chemical Company, Inc. (JP) | 2019-07-10 | — | — | EP | disclosed |
| EP-3508516-A1 | VULCANIZED RUBBER COMPOSITION AND PRODUCTION PROCESS THEREFOR | Mitsubishi Gas Chemical Company, Inc. (JP) | 2019-07-10 | — | — | EP | disclosed |
| US-5422360-A | Hydrazonoimidazolidin-4-one derivatives; treatment of diabetes and aging disorders | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-06-06 | — | — | US | disclosed |
| US-5272165-A | 2-alkylidene-aminoguanidines and methods of use therefor | THE ROCKEFELLER UNIVERSITY (US) | 1993-12-21 | — | — | US | disclosed |
| US-5243071-A | Acetoacetic acid guanyl hydrazone; inhibits food spoilage and protein aging | THE ROCKEFELLER UNIVERSITY (US) | 1993-09-07 | — | — | US | disclosed |
| EP-0531812-A1 | Maillard reaction inhibitor, process for producing it, composition containing it and the use thereof | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-03-17 | — | — | EP | disclosed |
| WO-1992019236-A1 | 2-ALKYLIDENE-AMINOGUANIDINES FOR INHIBITING ADVANCED NONENZYMATICGLYCOSYLATION OF PROTEINS | THE ROCKEFELLER UNIVERSITY (US) | 1992-11-12 | — | — | WO | disclosed |
| US-5130324-A | For inhibiting nonezymatic crosslinking of glycosylation products of proteins | THE ROCKEFELLER UNIVERSITY (US) | 1992-07-14 | — | — | US | disclosed |