Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 20/20 | 0.55 |
| ▸ | ADORA1 | P30542 | 20/20 | 0.55 |
| ▸ | ADORA2A | P29274 | 11/20 | 0.52 |
| ▸ | HTR2C | P28335 | 3/20 | 0.48 |
| ▸ | HTR2B | P41595 | 3/20 | 0.48 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | TSPO | P30536 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29574519 | 0.89 | ADORA3 (0.54) | ADORA3ADORA1ADORA2AHTR2CHTR2B | |
| SCHEMBL29573460 | 0.83 | ADORA3 (0.39) | ADORA3ADORA1ADORA2AHTR2CHTR2B | |
| SCHEMBL29573308 | 0.81 | ADORA3 (0.78) | ADORA3ADORA1ADORA2AHTR2CHTR2B | |
| SCHEMBL29574294 | 0.80 | ADORA3 (0.52) | ADORA3ADORA1ADORA2AHTR2CHTR2B | |
| SCHEMBL29575015 | 0.80 | ADORA3 (0.57) | ADORA3ADORA1ADORA2AHTR2CHTR2B | |
| SCHEMBL29573464 | 0.79 | ADORA3 (0.69) | ADORA3ADORA1ADORA2AHTR2CHTR2B | |
| SCHEMBL29573997 | 0.74 | ADORA3 (0.66) | ADORA3ADORA1ADORA2AHTR2CHTR2B | |
| SCHEMBL29573618 | 0.74 | ADORA3 (0.39) | ADORA3ADORA1ADORA2AHTR2CHTR2B | |
| SCHEMBL23201572 | 0.71 | ADORA3 (0.77) | ADORA3ADORA1ADORA2AHTR2CHTR2B | |
| SCHEMBL31754242 | 0.71 | ADORA3 (0.77) | ADORA3ADORA1ADORA2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116457356-A | A3 adenosine receptor agonists for use in medicine | 生物干预公司 | 2023-07-18 | — | — | CN | disclosed |
| EP-4196219-A1 | A3 ADENOSINE RECEPTOR AGONISTS FOR USE IN MEDICINE | Biointervene, Inc. (US) | 2023-06-21 | — | — | EP | disclosed |
| WO-2022040241-A1 | A3 ADENOSINE RECEPTOR AGONISTS FOR USE IN MEDICINE | BIOINTERVENE, INC. (US) | 2022-02-24 | — | — | WO | disclosed |