Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | BRS3 | P32247 | 1/20 | 0.40 |
| ▸ | POLQ | O75417 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ASPH | Q12797 | 1/20 | 0.39 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.39 |
| ▸ | BAD | Q92934 | 2/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22717931 | 1.00 | DHODH (0.42) | DHODHGPR35PTGESBRS3POLQ | |
| SCHEMBL22717370 | 0.87 | NMT1 (0.46) | — | |
| SCHEMBL29574997 | 0.83 | DHODH (0.47) | DHODHGPR35BRS3POLQPPARD | |
| SCHEMBL22717287 | 0.83 | DHODH (0.47) | DHODHGPR35BRS3POLQPPARD | |
| SCHEMBL22717565 | 0.80 | DHODH (0.42) | DHODHGPR35BRS3XDHPPARD | |
| SCHEMBL29575407 | 0.80 | DHODH (0.42) | DHODHGPR35BRS3XDHPPARD | |
| SCHEMBL30282681 | 0.80 | GPR35 (0.46) | DHODHGPR35POLQXDHPPARD | |
| SCHEMBL22717406 | 0.80 | GPR35 (0.46) | DHODHGPR35POLQXDHPPARD | |
| SCHEMBL29573949 | 0.80 | GPR35 (0.46) | DHODHGPR35POLQXDHPPARD | |
| SCHEMBL22717468 | 0.76 | GPR35 (0.49) | DHODHGPR35BRS3POLQKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3976608-A1 | THIADIAZOLYL DERIVATIVES AS DNA POLYMERASE THETA INHIBITORS | Ideaya Biosciences, Inc. (US) | 2022-04-06 | — | — | EP | disclosed |