Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 17/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 14/20 | 0.53 |
| ▸ | HTR2B | P41595 | 3/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.53 |
| ▸ | HRH2 | P25021 | 1/20 | 0.52 |
| ▸ | HTR5A | P47898 | 1/20 | 0.52 |
| ▸ | TMIGD3 | P0DMS9 | 2/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.46 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26969055 | 0.94 | HRH2 (0.49) | ADORA3ADORA1HTR2BSLC6A3HRH2 | |
| SCHEMBL29573920 | 0.94 | HRH2 (0.52) | ADORA3ADORA1HTR2BSLC6A3HRH2 | |
| SCHEMBL29573437 | 0.91 | HRH2 (0.51) | ADORA3ADORA1HTR2BSLC6A3HRH2 | |
| SCHEMBL29574766 | 0.91 | HRH2 (0.51) | ADORA3ADORA1HTR2BSLC6A3HRH2 | |
| SCHEMBL29573475 | 0.89 | HRH2 (0.49) | ADORA3ADORA1HTR2BSLC6A3HRH2 | |
| SCHEMBL29573869 | 0.88 | HRH2 (0.52) | ADORA3ADORA1HTR2BSLC6A3HRH2 | |
| SCHEMBL29573861 | 0.88 | HRH2 (0.53) | ADORA3ADORA1HTR2BHRH2HTR5A | |
| SCHEMBL29573817 | 0.86 | HSP90B1 (0.52) | ADORA3ADORA1HTR2BHRH2HTR5A | |
| SCHEMBL29575011 | 0.84 | ADORA3 (0.70) | ADORA3ADORA1HTR2BSLC6A3TMIGD3 | |
| SCHEMBL26969054 | 0.84 | ADORA3 (0.70) | ADORA3ADORA1HTR2BSLC6A3TMIGD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4196219-A1 | A3 ADENOSINE RECEPTOR AGONISTS FOR USE IN MEDICINE | Biointervene, Inc. (US) | 2023-06-21 | — | — | EP | disclosed |
| WO-2022040241-A1 | A3 ADENOSINE RECEPTOR AGONISTS FOR USE IN MEDICINE | BIOINTERVENE, INC. (US) | 2022-02-24 | — | — | WO | disclosed |