SCHEMBL29574366

SCHEMBL29574366

NCc1ccc(-c2ccc(CN)s2)s1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 1/20 0.68
CYP2A6 P11509 13/20 0.67
CYP2B6 P20813 12/20 0.67
CYP2C19 P33261 12/20 0.67
CYP2E1 P05181 12/20 0.67
CYP3A4 P08684 11/20 0.67
CYP2C9 P11712 10/20 0.67
CYP2D6 P10635 9/20 0.55
CYP1A2 P05177 10/20 0.48
CYP2C8 P10632 7/20 0.48
LOX P28300 5/20 0.41
LOXL2 Q9Y4K0 2/20 0.41
MAOA P21397 1/20 0.41
MEN1 O00255 1/20 0.39
ALDH1A1 P00352 1/20 0.39
GLA P06280 1/20 0.39
MAPT P10636 1/20 0.39
HPGD P15428 1/20 0.39
KMT2A Q03164 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iodide SCHEMBL29574376 0.97 LTA4H (0.65) LTA4HCYP2A6CYP2B6CYP2C19CYP2E1
SCHEMBL2690127 0.82 LTA4H (1.00) LTA4HCYP2A6CYP2B6CYP2C19CYP2E1
SCHEMBL2690207 0.81 CYP2E1 (1.00) LTA4HCYP2A6CYP2B6CYP2C19CYP2E1
SCHEMBL30758544 0.81 LTA4H (0.50) LTA4HCYP2A6CYP2B6CYP2C19CYP2E1
SCHEMBL9200282 0.81 LTA4H (0.96) LTA4HCYP2A6CYP2B6CYP2C19CYP2E1
Iodide SCHEMBL28780492 0.81 LTA4H (0.96) LTA4HCYP2A6CYP2B6CYP2C19CYP2E1
Iodide SCHEMBL30758524 0.79 LTA4H (0.49) LTA4HCYP2A6CYP2B6CYP2C19CYP2E1
Hydrochloric Acid SCHEMBL31558446 0.79 CYP2A6 (0.96) LTA4HCYP2A6CYP2B6CYP2C19CYP2E1
SCHEMBL19531540 0.78 CYP2A6 (0.66) LTA4HCYP2A6CYP2B6CYP2C19CYP2E1
SCHEMBL6698000 0.78 CYP2A6 (0.56) LTA4HCYP2A6CYP2B6CYP2C19CYP2E1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109713133-B Organic-inorganic mixed perovskite compound, preparation method and application thereof 南开大学 2022-05-10 CN disclosed