Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.50 |
| ▸ | PAM | P19021 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | HTR2A | P28223 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL625625 | 0.97 | IDO1 (0.52) | IDO1PAMMAOBHTR2AMEN1 | |
| SCHEMBL1919743 | 0.97 | IDO1 (0.52) | IDO1PAMMAOBHTR2AMEN1 | |
| SCHEMBL250822 | 0.97 | IDO1 (0.52) | IDO1PAMMAOBHTR2AMEN1 | |
| SCHEMBL11024500 | 0.95 | IDO1 (0.50) | IDO1PAMMAOBHTR2AMEN1 | |
| SCHEMBL11739996 | 0.95 | IDO1 (0.50) | IDO1PAMMAOBHTR2AMEN1 | |
| SCHEMBL2957520 | 0.95 | IDO1 (0.50) | IDO1PAMMAOBHTR2AMEN1 | |
| SCHEMBL11024503 | 0.95 | IDO1 (0.50) | IDO1PAMMAOBHTR2AMEN1 | |
| Propene SCHEMBL2405130 | 0.87 | HTR2A (0.46) | IDO1PAMMAOBHTR2AMEN1 | |
| SCHEMBL10880315 | 0.87 | IDO1 (0.44) | IDO1PAMMAOBHTR2AMEN1 | |
| Propene SCHEMBL2405128 | 0.87 | HTR2A (0.46) | IDO1PAMMAOBHTR2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7763741-B2 | Separation of ginkgolides and bilobalide from G. biloba | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2010-07-27 | — | — | US | disclosed |
| US-20080108837-A1 | Separation Of Ginkgolides And Bilobalide From G. Biloba | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2008-05-08 | — | — | US | disclosed |
| WO-2005046829-A2 | SEPARATION OF GINKGOLIDES AND BILOBALIDE FROM G. BILOBA | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2005-05-26 | — | — | WO | disclosed |