SCHEMBL625625

SCHEMBL625625

BrC/C=C/c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.52
PAM P19021 1/20 0.52
MAOB P27338 2/20 0.50
HTR2A P28223 3/20 0.48
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
SIGMAR1 Q99720 2/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
KDM4E B2RXH2 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL250822 1.00 IDO1 (0.52) IDO1PAMMAOBHTR2AMEN1
SCHEMBL1919743 1.00 IDO1 (0.52) IDO1PAMMAOBHTR2AMEN1
SCHEMBL2957520 0.97 IDO1 (0.50) IDO1PAMMAOBHTR2AMEN1
SCHEMBL11024500 0.97 IDO1 (0.50) IDO1PAMMAOBHTR2AMEN1
SCHEMBL11739996 0.97 IDO1 (0.50) IDO1PAMMAOBHTR2AMEN1
SCHEMBL2957519 0.97 IDO1 (0.50) IDO1PAMMAOBHTR2AMEN1
SCHEMBL11024503 0.97 IDO1 (0.50) IDO1PAMMAOBHTR2AMEN1
SCHEMBL10880315 0.89 IDO1 (0.44) IDO1PAMMAOBHTR2AMEN1
Propene SCHEMBL2405130 0.89 HTR2A (0.46) IDO1PAMMAOBHTR2AMEN1
Propene SCHEMBL2405128 0.89 HTR2A (0.46) IDO1PAMMAOBHTR2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2174 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12391704-B2 Method for synthesizing decursin derivative PRG S&TECH INC. (KR) 2025-08-19 US claimed
CN-120058618-A Antitumor cinnamyl piperazine and 2-phenylbenzimidazole conjugate, and preparation method and application thereof 天津科技大学 2025-05-30 CN claimed
CN-119219575-B Antitumor cinnamyl piperazine resveratrol conjugate or pharmaceutically acceptable salt thereof, and preparation method and application thereof 天津科技大学 2025-03-11 CN claimed
CN-119390627-A Synthesis method of photocatalytic asymmetric thioether compound 中国人民解放军军事科学院防化研究院 2025-02-07 CN claimed
CN-119219575-A Antitumor cinnamyl piperazine resveratrol conjugate or pharmaceutically acceptable salt thereof, and preparation method and application thereof 天津科技大学 2024-12-31 CN claimed
CN-114867728-B New method for synthesizing decursin derivative PRG科技株式会社 2024-07-23 CN claimed
EP-4083045-B1 NOVEL METHOD FOR SYNTHESIZING DECURSIN DERIVATIVE PRG S&TECH INC (KR) 2023-12-13 EP claimed
CN-117142917-A Method for synthesizing chiral 4-substituted 3-alkoxycarbonyl butyrolactone derivative by palladium-catalyzed asymmetric hydrogenation 中国科学院大连化学物理研究所 2023-12-01 CN claimed
US-20230063754-A1 NOVEL METHOD FOR SYNTHESIZING DECURSIN DERIVATIVE PRG S&TECH INC. (KR) 2023-03-02 US claimed
EP-4083045-A1 NOVEL METHOD FOR SYNTHESIZING DECURSIN DERIVATIVE PRG S&Tech Inc. (KR) 2022-11-02 EP claimed
EP-0440329-A1 S-substituted carbonyl substituted betathioacrylamide biocides and fungicides ROHM AND HAAS COMPANY (US) 1991-08-07 EP claimed
EP-0149553-B1 NEGATIVE PHOTORESIST SYSTEMS ROHM AND HAAS COMPANY (US) 1991-05-15 EP claimed
EP-0341065-A2 Immunostimulating guanine dervatives, compositions and methods SCRIPPS CLINIC AND RESEARCH FOUNDATION (US) 1989-11-08 EP claimed
US-4631249-A IMIDIZATION OF POLYMETHYLMETHACRYLATE ROHM & HAAS COMPANY (US) 1986-12-23 US claimed
US-4569897-A IMIDIZED ACRYLIC POLYMERS AND CROSSLINKING AZIDE PHOTOSENSITIZER IN A SOLVENT ROHM AND HAAS COMPANY (US) 1986-02-11 US claimed
EP-0149553-A2 Negative photoresist systems ROHM AND HAAS COMPANY (US) 1985-07-24 EP claimed
US-4366331-A Process for production of 2,6-di-tert-alkenyl phenols THE GOODYEAR TIRE & RUBBER COMPANY (US) 1982-12-28 US claimed
US-4025695-A LAMINATION EXXON RESEARCH AND ENGINEERING COMPANY (US) 1977-05-24 US claimed
US-3985832-A BY REACTING CHLORINATED RUBBER WITH A BROMINE OR IODINE COMPOUND EXXON RESEARCH AND ENGINEERING COMPANY (US) 1976-10-12 US claimed
US-3968094-A Photodegradable plastics containing haloolefins THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF AGRICULTURE (US) 1976-07-06 US claimed