SCHEMBL29577658

SCHEMBL29577658

N=C(N)NCCC[C@H](NC(=O)[C@@H]1CC2CCCCC2N1)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ EED O75530 3/20 0.44
▸ CTSC P53634 7/20 0.39
▸ EPHX2 P34913 2/20 0.36
▸ SMN1; SMN2 Q16637 1/20 0.36
▸ PRMT5 O14744 1/20 0.36
▸ WDR77 Q9BQA1 1/20 0.36
▸ C3AR1 Q16581 1/20 0.33
▸ CPB2 Q96IY4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27572870 1.00 EED (0.44) EEDCTSCEPHX2SMN1; SMN2PRMT5
SCHEMBL27572862 1.00 EED (0.44) EEDCTSCEPHX2SMN1; SMN2PRMT5
Acetic Acid SCHEMBL22639110 0.97 EED (0.44) EEDCTSCEPHX2SMN1; SMN2PRMT5
Acetic Acid SCHEMBL22639109 0.97 EED (0.44) EEDCTSCEPHX2SMN1; SMN2PRMT5
Arginine SCHEMBL30096925 0.83 DDAH1 (0.37) EEDCTSCPRMT5WDR77
SCHEMBL10650846 0.81 MEN1 (0.44) CTSCEPHX2SMN1; SMN2
SCHEMBL29421098 0.81 MEN1 (0.44) CTSCEPHX2SMN1; SMN2
SCHEMBL30310981 0.80 EED (0.46) EEDCTSCEPHX2
SCHEMBL6561158 0.80 GRIN1 (0.44) EPHX2SMN1; SMN2
SCHEMBL17711236 0.80 MEN1 (0.47) CTSCEPHX2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12492422-B2 Ex vivo protease activity detection for disease detection/diagnostic, staging, monitoring and treatment Sunbird Bio, Inc. (US) 2025-12-09 — — US disclosed
CN-111971293-B Peptide synthesis method JITSUBO株式会社 2024-07-30 — — CN disclosed
CN-107406480-B Peptide synthesis method JITSUBO株式会社 2022-06-24 — — CN disclosed
US-20220128567-A1 EX VIVO PROTEASE ACTIVITY DETECTION FOR DISEASE DETECTION/DIAGNOSTIC, STAGING, MONITORING AND TREATMENT Sunbird Bio, Inc. 2022-04-28 — — US disclosed
EP-3982991-A2 NRP-1 BINDING INHIBITORY PEPTIDES AND USES THEREOF INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) 2022-04-20 — — EP disclosed
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