Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | ALPI | P09923 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | XIAP | P98170 | 1/20 | 0.50 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.50 |
| ▸ | CPA3 | P15088 | 3/20 | 0.47 |
| ▸ | CPA1 | P15085 | 2/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | CPB1 | P15086 | 1/20 | 0.47 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.47 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6285590 | 1.00 | CYP1A2 (0.53) | CYP1A2ALPIPKMPTGS1XIAP | |
| SCHEMBL8894219 | 1.00 | CYP1A2 (0.53) | CYP1A2ALPIPKMPTGS1XIAP | |
| SCHEMBL28344978 | 0.84 | LDHA (0.59) | ALDH1A1 | |
| SCHEMBL31020736 | 0.84 | CNR2 (0.50) | — | |
| SCHEMBL9452688 | 0.82 | PPARG (0.52) | CYP1A2ALPIPKMPTGS1XIAP | |
| SCHEMBL30302031 | 0.82 | KDM6B (0.55) | CYP1A2PKMPTGS1SLC7A5HSD17B10 | |
| SCHEMBL31020732 | 0.82 | PPARG (0.45) | CYP1A2ALPIPKMPTGS1XIAP | |
| SCHEMBL4964530 | 0.81 | CYP1A2 (0.50) | CYP1A2ALPIPKMPTGS1XIAP | |
| SCHEMBL4964528 | 0.81 | CYP1A2 (0.50) | CYP1A2ALPIPKMPTGS1XIAP | |
| SCHEMBL29065936 | 0.81 | CYP1A2 (0.50) | CYP1A2ALPIPKMPTGS1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3982980-A1 | NEOANTIGEN COMPOSITIONS AND USES THEREOF | BioNTech US Inc. (US) | 2022-04-20 | — | — | EP | disclosed |