Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF18A | Q8NI77 | 20/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22964659 | 1.00 | KIF18A (0.68) | KIF18A | |
| SCHEMBL22964485 | 0.81 | KIF18A (1.00) | KIF18A | |
| SCHEMBL22148435 | 0.81 | KIF18A (0.70) | KIF18A | |
| SCHEMBL29370895 | 0.81 | KIF18A (0.70) | KIF18A | |
| SCHEMBL31047339 | 0.81 | KIF18A (0.51) | KIF18A | |
| SCHEMBL31047348 | 0.81 | KIF18A (0.47) | KIF18A | |
| SCHEMBL24318989 | 0.80 | KIF18A (0.70) | KIF18A | |
| SCHEMBL29609024 | 0.80 | KIF18A (0.70) | KIF18A | |
| SCHEMBL31047358 | 0.80 | KIF18A (0.47) | KIF18A | |
| SCHEMBL31373529 | 0.79 | KIF18A (0.48) | KIF18A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4007752-A1 | KIF18A INHIBITORS | Amgen Inc. (US) | 2022-06-08 | — | — | EP | disclosed |