Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 15/20 | 0.59 |
| ▸ | CTSD | P07339 | 1/20 | 0.59 |
| ▸ | BACE2 | Q9Y5Z0 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29579768 | 0.93 | BACE1 (0.60) | BACE1CTSDBACE2 | |
| SCHEMBL30607497 | 0.90 | BACE1 (0.66) | BACE1CTSDBACE2 | |
| SCHEMBL30799896 | 0.88 | BACE1 (0.66) | BACE1CTSDBACE2 | |
| SCHEMBL30130349 | 0.87 | BACE1 (0.60) | BACE1CTSDBACE2 | |
| SCHEMBL30198937 | 0.85 | BACE1 (0.73) | BACE1CTSDBACE2 | |
| SCHEMBL29383336 | 0.84 | BACE1 (0.56) | BACE1CTSDBACE2 | |
| SCHEMBL30799525 | 0.84 | BACE1 (0.58) | BACE1CTSDBACE2 | |
| SCHEMBL29605864 | 0.84 | BACE1 (0.65) | BACE1CTSDBACE2 | |
| SCHEMBL30193015 | 0.84 | BACE1 (0.53) | BACE1CTSDBACE2 | |
| SCHEMBL30974088 | 0.83 | BACE1 (0.62) | BACE1CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12043674-B2 | Synthetic cyclic peptides and methods of preparation and use thereof | AUBURN UNIVERSITY (US) | 2024-07-23 | — | — | US | disclosed |
| US-20220119445-A1 | SYNTHETIC CYCLIC PEPTIDES AND METHODS OF PREPARATION AND USE THEREOF | NATIONAL SCIENCE FOUNDATION | 2022-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12043674-B2 | Synthetic cyclic peptides and methods of preparation and use thereof | VIP, PTMS, IAPP | BACE1 464/4885CTSD 2260/4885BACE2 2584/4885 |
| US-20220119445-A1 | SYNTHETIC CYCLIC PEPTIDES AND METHODS OF PREPARATION AND USE THEREOF | VIP, PTMS, IAPP | BACE1 464/4885CTSD 2260/4885BACE2 2584/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.