⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7391293 | 1.00 | KMT2A (0.33) | — | |
| SCHEMBL35115 | 1.00 | KMT2A (0.33) | — | |
| SCHEMBL70819 | 0.97 | — | — | |
| SCHEMBL542776 | 0.94 | KMT2A (0.36) | — | |
| SCHEMBL9956415 | 0.94 | KMT2A (0.36) | — | |
| SCHEMBL25327994 | 0.94 | KMT2A (0.36) | — | |
| SCHEMBL13858690 | 0.94 | KMT2A (0.36) | — | |
| SCHEMBL11594630 | 0.94 | KMT2A (0.36) | — | |
| SCHEMBL7737845 | 0.94 | KMT2A (0.36) | — | |
| SCHEMBL7992221 | 0.94 | KMT2A (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1346 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014028669-A1 | NOVEL COMPOUNDS FOR MODULATION OF ROR-GAMMA ACTIVITY | BIOGEN IDEC MA INC. (US) | 2014-02-20 | — | — | WO | claimed |
| US-20120184556-A1 | SUBSTITUTED ENZOIMIDAZOLESULFONAMIDES AND SUBSTITUTED INDOLESULFONAMIDES AS MGLUR4 POTENTIATORS | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2012-07-19 | — | — | US | claimed |
| EP-2456310-A1 | SUBSTITUTED BENZOIMIDAZOLESULFONAMIDES AND SUBSTITUTED INDOLESULFONAMIDES AS MGLUR4 POTENTIATORS | Vanderbilt University (US) | 2012-05-30 | — | — | EP | claimed |
| WO-2011011722-A1 | SUBSTITUTED BENZOIMIDAZOLESULFONAMIDES AND SUBSTITUTED INDOLESULFONAMIDES AS MGLUR4 POTENTIATORS | VANDERBILT UNIVERSITY (US) | 2011-01-27 | — | — | WO | claimed |
| US-20090256468-A1 | Novel organic electroluminescent compounds and organic electroluminescent device using the same | GRACEL DISPLAY INC. (KR) | 2009-10-15 | — | — | US | claimed |
| US-20090230852-A1 | Novel organic electroluminescent compounds and organic electroluminescent device using the same | GRACEL DISPLAY INC. (KR) | 2009-09-17 | — | — | US | claimed |
| EP-2100941-A2 | Novel organic electroluminescent compounds and organic electroluminescent device using the same | Gracel Display Inc. (KR) | 2009-09-16 | — | — | EP | claimed |
| EP-2096108-A1 | Novel organic electroluminescent compounds and organic electroluminscent device using the same | Gracel Display Inc. (KR) | 2009-09-02 | — | — | EP | claimed |
| EP-1399431-B1 | NOVEL NITRILES USEFUL AS REVERSIBLE INHIBITORS OF CYSTEINE PROTEASES | BOEHRINGER INGELHEIM PHARMA (US) | 2009-02-18 | — | — | EP | claimed |
| US-6982263-B2 | Nitriles useful as reversible inhibitors of cysteine proteases | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2006-01-03 | — | — | US | claimed |
| US-20040152132-A1 | Solid phase synthesis of LXR ligands | TULARIK INC. | 2004-08-05 | — | — | US | claimed |
| US-6673543-B2 | JOINING LIVER RECEPTORS TO SOLID SUPPORT; GENERATE SOLID SUPPORT, JOIN ANILINE DERIVATIVE TO SUPPORT, INCUBATE WITH ALDEHYE, KETONE, INCUBATE ANILINE DERIVATIVE WITH ACYLATING AGENT, RECOVER SUPPORT | TULARIK, INC. | 2004-01-06 | — | — | US | claimed |
| US-20030119827-A1 | Novel nitriles useful as reversible inhibitors of cysteine proteases | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2003-06-26 | — | — | US | claimed |
| WO-2002100849-A2 | NOVEL NITRILES USEFUL AS REVERSIBLE INHIBITORS OF CYSTEINE PROTEASES | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2002-12-19 | — | — | WO | claimed |
| US-20020072073-A1 | Solid phase synthesis of LXR ligands | AMGEN INC. | 2002-06-13 | — | — | US | claimed |
| WO-2001077067-A2 | SOLID PHASE SYNTHESIS OF LXR LIGANDS | TULARIK INC. (US) | 2001-10-18 | — | — | WO | claimed |
| US-5294531-A | BicycloUm.n.oealkane-1-ylcarbonylacetamide compound | FUJI PHOTO FILM CO., LTD. (JP) | 1994-03-15 | — | — | US | claimed |
| WO-2024149340-A1 | INDOLONE DERIVATIVE HAVING IRAK4 INHIBITORY ACTIVITY, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 深圳众格生物科技有限公司 | 2024-07-18 | — | — | WO | disclosed |
| EP-0268554-A2 | 1,5-Diphenyl pyrazole-3-carbonic-acid derivatives for the protection of cultured plants | CIBA-GEIGY AG (CH) | 1988-05-25 | — | — | EP | disclosed |
| EP-0191736-A2 | Use of quinoline derivatives for the protection of crop plants | CIBA-GEIGY AG (CH) | 1986-08-20 | — | — | EP | disclosed |