⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL295795 | 0.97 | — | — | |
| SCHEMBL7391293 | 0.97 | KMT2A (0.33) | — | |
| SCHEMBL35115 | 0.97 | KMT2A (0.33) | — | |
| SCHEMBL316141 | 0.94 | CA1 (0.33) | — | |
| SCHEMBL104445 | 0.94 | CA1 (0.33) | — | |
| SCHEMBL25391815 | 0.90 | — | — | |
| SCHEMBL13858690 | 0.90 | KMT2A (0.36) | — | |
| SCHEMBL11594630 | 0.90 | KMT2A (0.36) | — | |
| SCHEMBL7340365 | 0.90 | KMT2A (0.36) | — | |
| SCHEMBL9956415 | 0.90 | KMT2A (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1535 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116396278-A | Carbazole derivatives as dopamine D3 receptor selectivity modulators | 北京大学 | 2023-07-07 | — | — | CN | claimed |
| CN-113072521-A | ROR gamma t inhibitor and application thereof in medicine | 广东东阳光药业有限公司 | 2021-07-06 | — | — | CN | claimed |
| WO-2014028669-A1 | NOVEL COMPOUNDS FOR MODULATION OF ROR-GAMMA ACTIVITY | BIOGEN IDEC MA INC. (US) | 2014-02-20 | — | — | WO | claimed |
| US-20120184556-A1 | SUBSTITUTED ENZOIMIDAZOLESULFONAMIDES AND SUBSTITUTED INDOLESULFONAMIDES AS MGLUR4 POTENTIATORS | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2012-07-19 | — | — | US | claimed |
| EP-2456310-A1 | SUBSTITUTED BENZOIMIDAZOLESULFONAMIDES AND SUBSTITUTED INDOLESULFONAMIDES AS MGLUR4 POTENTIATORS | Vanderbilt University (US) | 2012-05-30 | — | — | EP | claimed |
| WO-2011011722-A1 | SUBSTITUTED BENZOIMIDAZOLESULFONAMIDES AND SUBSTITUTED INDOLESULFONAMIDES AS MGLUR4 POTENTIATORS | VANDERBILT UNIVERSITY (US) | 2011-01-27 | — | — | WO | claimed |
| US-20100130498-A1 | AGONISTS OF BITTER TASTE RECEPTORS AND USES THEREOF | DEUTSHES INSTITUT FUR ERNAHRUNGSFORSCHUNG POTSDAM- REHBRUCKE (DE) | 2010-05-27 | — | — | US | claimed |
| EP-2132564-A2 | AGONISTS OF BITTER TASTE RECEPTORS AND USES THEREOF | Deutsches Institut für Ernährungsforschung Potsdam -Rehbrücke Stiftung des Öffentlichen Rechts (DE) | 2009-12-16 | — | — | EP | claimed |
| US-20090256468-A1 | Novel organic electroluminescent compounds and organic electroluminescent device using the same | GRACEL DISPLAY INC. (KR) | 2009-10-15 | — | — | US | claimed |
| EP-2096108-A1 | Novel organic electroluminescent compounds and organic electroluminscent device using the same | Gracel Display Inc. (KR) | 2009-09-02 | — | — | EP | claimed |
| WO-2008119527-A2 | AGONISTS OF BITTER TASTE RECEPTORS AND USES THEREOF | DEUTSCHES INSTITUT FÜR ERNÄHRUNGSFORSCHUNG POSTDAM-REHBRÜCKE STIFTUNG DES ÖFFENTLICHEN RECHTS (DE) | 2008-10-09 | — | — | WO | claimed |
| EP-1975611-A1 | Agonists of bitter taste receptors and uses thereof | Deutsches Institut für Ernährungsforschung Potsdam -Rehbrücke-Stiftung des öffentlichen Rechts- Vertreten durch den Stiftungsvorstand (DE) | 2008-10-01 | — | — | EP | claimed |
| US-7361645-B2 | Androgenic 7-substituted 11-halogen steroids | BAYER SCHERING PHARMA AG (DE) | 2008-04-22 | — | — | US | claimed |
| US-6982263-B2 | Nitriles useful as reversible inhibitors of cysteine proteases | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2006-01-03 | — | — | US | claimed |
| US-20030119827-A1 | Novel nitriles useful as reversible inhibitors of cysteine proteases | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2003-06-26 | — | — | US | claimed |
| US-6531498-B1 | Antiallergens, etc | MERCK PATENTGESELLSCHAFT (DE) | 2003-03-11 | — | — | US | claimed |
| WO-2002100849-A2 | NOVEL NITRILES USEFUL AS REVERSIBLE INHIBITORS OF CYSTEINE PROTEASES | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2002-12-19 | — | — | WO | claimed |
| US-5294531-A | BicycloUm.n.oealkane-1-ylcarbonylacetamide compound | FUJI PHOTO FILM CO., LTD. (JP) | 1994-03-15 | — | — | US | claimed |
| US-4927902-A | REACTION PRODUCT OF HYDROGEN SULFIDE OR ORGANIC DITHIOLS WITH POLYGLYCIDYL SUBSTITUTED AMINES | HENKEL CORPORATION (US) | 1990-05-22 | — | — | US | claimed |
| EP-0329093-A2 | Polythiols and use as epoxy resin curing agents | HENKEL CORPORATION (a Delaware corp.) (US) | 1989-08-23 | — | — | EP | claimed |