Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 8/20 | 0.48 |
| ▸ | MAPT | P10636 | 7/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL263614 | 1.00 | PKM (0.54) | PKML3MBTL1MAPTTDP1ALDH1A1 | |
| SCHEMBL267940 | 0.91 | PKM (0.53) | PKML3MBTL1MAPTTDP1ALDH1A1 | |
| SCHEMBL15674547 | 0.87 | PKM (0.49) | PKML3MBTL1MAPTTDP1ALDH1A1 | |
| SCHEMBL30338496 | 0.85 | PKM (0.61) | PKML3MBTL1MAPTTDP1ALDH1A1 | |
| SCHEMBL21794169 | 0.85 | PKM (0.61) | PKML3MBTL1MAPTTDP1ALDH1A1 | |
| SCHEMBL23677862 | 0.85 | PKM (0.61) | PKML3MBTL1MAPTTDP1ALDH1A1 | |
| SCHEMBL29440624 | 0.84 | PKM (0.56) | PKML3MBTL1MAPTTDP1ALDH1A1 | |
| SCHEMBL972013 | 0.84 | PKM (0.56) | PKML3MBTL1MAPTTDP1ALDH1A1 | |
| SCHEMBL18053754 | 0.84 | PKM (0.56) | PKML3MBTL1MAPTTDP1ALDH1A1 | |
| SCHEMBL14402360 | 0.81 | HPGD (0.47) | L3MBTL1MAPTTDP1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110167946-B | Sulfonamide compounds having TNAP inhibitory activity | 第一三共株式会社 | 2022-04-08 | — | — | CN | disclosed |