Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRB2 | P62993 | 1/20 | 0.44 |
| ▸ | CMA1 | P23946 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 2/20 | 0.41 |
| ▸ | XIAP | P98170 | 1/20 | 0.41 |
| ▸ | REN | P00797 | 1/20 | 0.41 |
| ▸ | CALCRL | Q16602 | 3/20 | 0.41 |
| ▸ | RAMP1 | O60894 | 1/20 | 0.41 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | PREP | P48147 | 1/20 | 0.39 |
| ▸ | FAP | Q12884 | 1/20 | 0.39 |
| ▸ | DPP3 | Q9NY33 | 1/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.39 |
| ▸ | NAA50 | Q9GZZ1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29579502 | 0.92 | ACE (0.43) | GRB2CMA1ACEXIAPREN | |
| SCHEMBL29464997 | 0.86 | GRB2 (0.42) | GRB2XIAPCALCRLRAMP1PTPN1 | |
| SCHEMBL29832826 | 0.86 | PTPN1 (0.43) | CMA1ACERENPTPN1ITGB1 | |
| SCHEMBL29580081 | 0.85 | POLB (0.39) | GRB2CMA1CALCRLRAMP1P2RY12 | |
| SCHEMBL30141679 | 0.85 | GRB2 (0.46) | GRB2XIAPDPP3 | |
| SCHEMBL31031620 | 0.85 | PREP (0.40) | GRB2CMA1XIAPCALCRLRAMP1 | |
| SCHEMBL29832765 | 0.83 | PTPN1 (0.42) | CMA1CALCRLRAMP1PTPN1ITGB1 | |
| SCHEMBL28463049 | 0.82 | GRB2 (0.51) | GRB2CMA1ACEXIAPREN | |
| SCHEMBL29641635 | 0.82 | GRB2 (0.60) | GRB2CMA1ACEXIAPREN | |
| SCHEMBL31426844 | 0.81 | GRB2 (0.44) | GRB2XIAPCALCRLRAMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12043674-B2 | Synthetic cyclic peptides and methods of preparation and use thereof | AUBURN UNIVERSITY (US) | 2024-07-23 | — | — | US | disclosed |
| US-20220119445-A1 | SYNTHETIC CYCLIC PEPTIDES AND METHODS OF PREPARATION AND USE THEREOF | NATIONAL SCIENCE FOUNDATION | 2022-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12043674-B2 | Synthetic cyclic peptides and methods of preparation and use thereof | VIP, PTMS, IAPP | GRB2 340/4885CMA1 1879/4885ACE 515/4885 |
| US-20220119445-A1 | SYNTHETIC CYCLIC PEPTIDES AND METHODS OF PREPARATION AND USE THEREOF | VIP, PTMS, IAPP | GRB2 340/4885CMA1 1879/4885ACE 515/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.