Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRB2 | P62993 | 1/20 | 0.42 |
| ▸ | NAA50 | Q9GZZ1 | 1/20 | 0.40 |
| ▸ | FAP | Q12884 | 2/20 | 0.39 |
| ▸ | CALCRL | Q16602 | 4/20 | 0.39 |
| ▸ | RAMP1 | O60894 | 1/20 | 0.39 |
| ▸ | XIAP | P98170 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | PREP | P48147 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | APLNR | P35414 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30493569 | 0.88 | NMUR2 (0.40) | GRB2NAA50CALCRLRAMP1PTPN1 | |
| SCHEMBL29580398 | 0.86 | GRB2 (0.44) | GRB2NAA50FAPCALCRLRAMP1 | |
| SCHEMBL29580081 | 0.85 | POLB (0.39) | GRB2FAPCALCRLRAMP1DPP4 | |
| SCHEMBL31544467 | 0.85 | APLNR (0.40) | GRB2NAA50FAPPTPN1APLNR | |
| SCHEMBL28890650 | 0.85 | APLNR (0.40) | GRB2NAA50FAPPTPN1APLNR | |
| SCHEMBL4726312 | 0.85 | APLNR (0.40) | GRB2NAA50FAPPTPN1APLNR | |
| SCHEMBL4726314 | 0.85 | APLNR (0.40) | GRB2NAA50FAPPTPN1APLNR | |
| SCHEMBL29579502 | 0.84 | ACE (0.43) | GRB2FAPCALCRLRAMP1XIAP | |
| SCHEMBL29832781 | 0.82 | APLNR (0.38) | GRB2NAA50FAPPTPN1APLNR | |
| SCHEMBL31670614 | 0.81 | CAPN1 (0.42) | CALCRLXIAPPTPN1SLC6A2STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112876578-B | Amphiphilic glucan derivative carrier targeting tumor-associated fibroblasts, and preparation and application of pharmaceutical composition of amphiphilic glucan derivative carrier | 中国药科大学 | 2022-03-18 | — | — | CN | claimed |
| CN-112876578-B | Amphiphilic glucan derivative carrier targeting tumor-associated fibroblasts, and preparation and application of pharmaceutical composition of amphiphilic glucan derivative carrier | 中国药科大学 | 2022-03-18 | — | — | CN | disclosed |