Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | GFER | P55789 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21641736 | 0.86 | KCNH2 (0.44) | KDM4EGAAMAPTGFERALDH1A1 | |
| SCHEMBL2729685 | 0.86 | KCNH2 (0.44) | KDM4EGAAMAPTGFERALDH1A1 | |
| SCHEMBL27393647 | 0.86 | KCNH2 (0.44) | KDM4EGAAMAPTGFERALDH1A1 | |
| SCHEMBL6619144 | 0.84 | MAPT (0.38) | SOS1GAAMAPTALDH1A1HRH4 | |
| SCHEMBL24352932 | 0.83 | KCNH2 (0.41) | SOS1HRH4KCNH2L3MBTL1 | |
| SCHEMBL6620926 | 0.82 | HRH4 (0.46) | KMT2AHRH4MEN1 | |
| SCHEMBL25889734 | 0.82 | CDK4 (0.38) | SOS1HRH4BRAFKCNH2CHRNA7 | |
| SCHEMBL21142813 | 0.81 | CHRNA7 (0.43) | KCNH2CHRNA7 | |
| SCHEMBL25646900 | 0.81 | CHRNA7 (0.43) | KCNH2CHRNA7 | |
| SCHEMBL29310682 | 0.79 | HSD11B1 (0.46) | KDM4EGAAHRH4SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114591334-B | Dihydropyrazolopyrimidinone derivatives | 山东轩竹医药科技有限公司 | 2023-10-20 | — | — | CN | disclosed |
| CN-114591334-A | Dihydropyrazolopyrimidinone derivatives | 山东轩竹医药科技有限公司 | 2022-06-07 | — | — | CN | disclosed |