Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HEXA | P06865 | 2/20 | 0.51 |
| ▸ | HEXB | P07686 | 2/20 | 0.51 |
| ▸ | LCK | P06239 | 1/20 | 0.51 |
| ▸ | BCHE | P06276 | 5/20 | 0.47 |
| ▸ | ACHE | P22303 | 5/20 | 0.47 |
| ▸ | MAOB | P27338 | 4/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.47 |
| ▸ | KDR | P35968 | 2/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | POLB | P06746 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29581319 | 0.99 | HEXA (0.52) | HEXAHEXBLCKBCHEACHE | |
| SCHEMBL29580991 | 0.94 | LCK (0.56) | HEXAHEXBLCKBCHEACHE | |
| SCHEMBL29580895 | 0.89 | MEN1 (0.56) | HEXAHEXBLCKBCHEACHE | |
| SCHEMBL29581473 | 0.88 | MEN1 (0.57) | HEXAHEXBLCKBCHEACHE | |
| SCHEMBL29581299 | 0.87 | LCK (0.52) | HEXAHEXBLCKMAOBMEN1 | |
| SCHEMBL29581961 | 0.86 | FGFR1 (0.43) | LCKBCHEACHEMAOBFGFR1 | |
| SCHEMBL29581868 | 0.85 | FGFR1 (0.44) | LCKBCHEACHEMAOBFGFR1 | |
| SCHEMBL29580722 | 0.82 | MEN1 (0.59) | HEXAHEXBLCKFGFR1KDR | |
| SCHEMBL29581465 | 0.80 | MEN1 (0.56) | HEXAHEXBLCKFGFR1KDR | |
| SCHEMBL3759174 | 0.79 | HEXA (0.60) | HEXAHEXBFGFR1KDRPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114591239-A | Naphthalimide derivative and synthesis and application thereof | 中国科学院大连化学物理研究所 | 2022-06-07 | — | — | CN | claimed |
| CN-114591239-A | Naphthalimide derivative and synthesis and application thereof | 中国科学院大连化学物理研究所 | 2022-06-07 | — | — | CN | disclosed |