Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 4/20 | 0.56 |
| ▸ | HEXA | P06865 | 2/20 | 0.53 |
| ▸ | HEXB | P07686 | 2/20 | 0.53 |
| ▸ | LCK | P06239 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.48 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29581473 | 0.99 | MEN1 (0.57) | MEN1KMT2APOLBHEXAHEXB | |
| SCHEMBL29580722 | 0.93 | MEN1 (0.59) | MEN1KMT2APOLBHEXAHEXB | |
| SCHEMBL29580559 | 0.89 | HEXA (0.51) | MEN1KMT2APOLBHEXAHEXB | |
| SCHEMBL29581319 | 0.88 | HEXA (0.52) | MEN1KMT2APOLBHEXAHEXB | |
| SCHEMBL29581442 | 0.86 | MEN1 (0.61) | MEN1KMT2APOLBHEXAHEXB | |
| SCHEMBL29582120 | 0.85 | MEN1 (0.49) | MEN1KMT2APOLBLCKALDH1A1 | |
| SCHEMBL26053794 | 0.84 | MEN1 (0.69) | MEN1KMT2APOLBHEXAHEXB | |
| SCHEMBL31094030 | 0.84 | MEN1 (0.69) | MEN1KMT2APOLBHEXAHEXB | |
| SCHEMBL29580611 | 0.84 | MEN1 (0.48) | MEN1KMT2APOLBLCKALDH1A1 | |
| SCHEMBL29580991 | 0.82 | LCK (0.56) | MEN1KMT2APOLBHEXAHEXB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114591239-A | Naphthalimide derivative and synthesis and application thereof | 中国科学院大连化学物理研究所 | 2022-06-07 | — | — | CN | claimed |
| CN-114591239-A | Naphthalimide derivative and synthesis and application thereof | 中国科学院大连化学物理研究所 | 2022-06-07 | — | — | CN | disclosed |