⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL574748 | 0.75 | — | — | |
| SCHEMBL9342945 | 0.64 | NISCH (0.33) | — | |
| SCHEMBL1249288 | 0.64 | — | — | |
| SCHEMBL28481228 | 0.62 | ALDH1A1 (0.33) | — | |
| SCHEMBL10670205 | 0.62 | ALDH1A1 (0.33) | — | |
| SCHEMBL449875 | 0.60 | — | — | |
| SCHEMBL157942 | 0.60 | — | — | |
| SCHEMBL11443030 | 0.60 | — | — | |
| SCHEMBL11443027 | 0.60 | — | — | |
| SCHEMBL11298086 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4232438-A1 | COMPOUNDS FOR THE TREATMENT OF ALZHEIMER'S DISEASE | The Governors of the University of Alberta (CA) | 2023-08-30 | — | — | EP | disclosed |
| WO-2022082305-A1 | COMPOUNDS FOR THE TREATMENT OF ALZHEIMER'S DISEASE | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2022-04-28 | — | — | WO | disclosed |