Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN2 | P17706 | 3/20 | 0.68 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.68 |
| ▸ | POLB | P06746 | 3/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.49 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8140569 | 0.90 | PTPN2 (0.68) | PTPN2PTPN1POLBSMN1; SMN2MAPT | |
| SCHEMBL12275828 | 0.87 | PTPN2 (0.61) | PTPN2PTPN1POLBSMN1; SMN2MAPT | |
| SCHEMBL23015486 | 0.86 | POLB (0.67) | PTPN2PTPN1POLBSMN1; SMN2MAPT | |
| SCHEMBL636579 | 0.84 | POLB (0.72) | PTPN2PTPN1POLBSMN1; SMN2MAPT | |
| SCHEMBL636578 | 0.84 | POLB (0.72) | PTPN2PTPN1POLBSMN1; SMN2MAPT | |
| SCHEMBL16457010 | 0.84 | POLB (0.72) | PTPN2PTPN1POLBSMN1; SMN2MAPT | |
| SCHEMBL636577 | 0.84 | POLB (0.72) | PTPN2PTPN1POLBSMN1; SMN2MAPT | |
| SCHEMBL27232172 | 0.83 | POLB (0.65) | PTPN2PTPN1POLBSMN1; SMN2MAPT | |
| SCHEMBL27228999 | 0.83 | POLB (0.65) | PTPN2PTPN1POLBSMN1; SMN2MAPT | |
| SCHEMBL17883904 | 0.82 | POLB (0.67) | PTPN2PTPN1POLBSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3995498-A1 | THIENOPYRIMIDINE DERIVATIVES HAVING STEREO CONFIGURATIONS AND USE THEREOF IN MEDICINE | Sunshine Lake Pharma Co., Ltd. (CN) | 2022-05-11 | — | — | EP | disclosed |