SCHEMBL29582266

SCHEMBL29582266

COc1ccc(CNc2nc(NCCN)nc3c2cnn3C)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
BCDIN3D Q7Z5W3 19/20 1.00
SHMT2 P34897 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22805424 1.00 BCDIN3D (1.00) BCDIN3DSHMT2
SCHEMBL13947042 0.90 BCDIN3D (0.82) BCDIN3DSHMT2
SCHEMBL13943303 0.89 BCDIN3D (0.81) BCDIN3DSHMT2
SCHEMBL13943296 0.88 BCDIN3D (0.79) BCDIN3DSHMT2
SCHEMBL13943317 0.88 BCDIN3D (0.78) BCDIN3DSHMT2
SCHEMBL13943304 0.88 BCDIN3D (0.78) BCDIN3DSHMT2
SCHEMBL22806010 0.85 BCDIN3D (1.00) BCDIN3DSHMT2
SCHEMBL29582423 0.85 BCDIN3D (1.00) BCDIN3DSHMT2
SCHEMBL22805563 0.85 BCDIN3D (1.00) BCDIN3D
SCHEMBL22806295 0.85 BCDIN3D (1.00) BCDIN3D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3986568-A1 BICYCLIC HETEROCYCLIC COMPOUNDS AS INHIBITORS OFBCDIN3D ACTIVITY Storm Therapeutics Ltd (GB) 2022-04-27 EP claimed
US-20220370453-A1 BICYCLIC HETEROCYCLIC COMPOUNDS AS INHIBITORS OF BCDIN3D ACTIVITY STORM THERAPEUTICS LIMITED (GB) 2022-11-24 US disclosed
EP-3986568-A1 BICYCLIC HETEROCYCLIC COMPOUNDS AS INHIBITORS OFBCDIN3D ACTIVITY Storm Therapeutics Ltd (GB) 2022-04-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220370453-A1 BICYCLIC HETEROCYCLIC COMPOUNDS AS INHIBITORS OF BCDIN3D ACTIVITY BCDIN3D, CDK3, CCNI BCDIN3D 1/4885SHMT2 1000/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.