Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCDIN3D | Q7Z5W3 | 10/20 | 0.81 |
| ▸ | SHMT2 | P34897 | 4/20 | 0.76 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.65 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.65 |
| ▸ | CDK2 | P24941 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13943317 | 0.94 | BCDIN3D (0.78) | BCDIN3DSHMT2CCNE2CCNE1CDK2 | |
| SCHEMBL13947042 | 0.90 | BCDIN3D (0.82) | BCDIN3DSHMT2 | |
| SCHEMBL22805424 | 0.89 | BCDIN3D (1.00) | BCDIN3DSHMT2 | |
| SCHEMBL29582266 | 0.89 | BCDIN3D (1.00) | BCDIN3DSHMT2 | |
| SCHEMBL13943296 | 0.88 | BCDIN3D (0.79) | BCDIN3DSHMT2 | |
| SCHEMBL13943304 | 0.88 | BCDIN3D (0.78) | BCDIN3DSHMT2 | |
| SCHEMBL13944728 | 0.87 | BCDIN3D (0.61) | BCDIN3DSHMT2 | |
| SCHEMBL13947365 | 0.87 | BCDIN3D (0.70) | BCDIN3DSHMT2CCNE2CCNE1CDK2 | |
| SCHEMBL13943324 | 0.86 | SHMT2 (1.00) | BCDIN3DSHMT2 | |
| SCHEMBL13947575 | 0.85 | BCDIN3D (0.70) | BCDIN3DSHMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009023978-A1 | PYRAZOLO [3,4 -D] PYRIMIDINE COMPOUNDS AND THEIR USE AS MODULATORS OF PROTEIN KINASE | ONCALIS AG (CH) | 2009-02-26 | — | — | WO | disclosed |
| EP-2025678-A1 | Pyrazolo[3,4-d]pyrimidine compounds and their use as modulators of protein kinase | Oncalis AG (CH) | 2009-02-18 | — | — | EP | disclosed |