Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK7 | P50613 | 15/20 | 0.70 |
| ▸ | CCNH | P51946 | 15/20 | 0.70 |
| ▸ | CCNK | O75909 | 12/20 | 0.70 |
| ▸ | CDK12 | Q9NYV4 | 12/20 | 0.70 |
| ▸ | CCNT1 | O60563 | 11/20 | 0.70 |
| ▸ | CCNE1 | P24864 | 11/20 | 0.70 |
| ▸ | CDK2 | P24941 | 11/20 | 0.70 |
| ▸ | CDK9 | P50750 | 11/20 | 0.70 |
| ▸ | MNAT1 | P51948 | 11/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | MAP2K5 | Q13163 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22076295 | 1.00 | CDK7 (0.70) | CDK7CCNHCCNKCDK12CCNT1 | |
| SCHEMBL22076293 | 1.00 | CDK7 (0.70) | CDK7CCNHCCNKCDK12CCNT1 | |
| SCHEMBL29584896 | 0.90 | CCNK (0.55) | CDK7CCNHCCNKCDK12CCNT1 | |
| SCHEMBL22076266 | 0.90 | CCNK (0.55) | CDK7CCNHCCNKCDK12CCNT1 | |
| SCHEMBL22076267 | 0.90 | CCNK (0.55) | CDK7CCNHCCNKCDK12CCNT1 | |
| SCHEMBL24145953 | 0.87 | CCNK (0.71) | CDK7CCNHCCNKCDK12CCNT1 | |
| SCHEMBL22076290 | 0.83 | CCNK (1.00) | CDK7CCNHCCNKCDK12CCNT1 | |
| SCHEMBL22076288 | 0.83 | CCNK (1.00) | CDK7CCNHCCNKCDK12CCNT1 | |
| SCHEMBL24308297 | 0.82 | CCNK (0.68) | CDK7CCNHCCNKCDK12CCNT1 | |
| SCHEMBL29492527 | 0.82 | CDK7 (0.80) | CDK7CCNHCCNKCDK12CCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4229038-A1 | DOSING REGIMENS FOR CYCLIN-DEPENDENT KINASE 7 (CDK7) INHIBITORS | Syros Pharmaceuticals, Inc. (US) | 2023-08-23 | — | — | EP | disclosed |
| WO-2022082056-A1 | DOSING REGIMENS FOR CYCLIN‑DEPENDENT KINASE 7 (CDK7) INHIBITORS | SYROS PHARMACEUTICALS, INC. (US) | 2022-04-21 | — | — | WO | disclosed |