Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNK | O75909 | 19/20 | 0.55 |
| ▸ | CDK12 | Q9NYV4 | 19/20 | 0.55 |
| ▸ | CCNT1 | O60563 | 17/20 | 0.55 |
| ▸ | CDK9 | P50750 | 17/20 | 0.55 |
| ▸ | CCNE1 | P24864 | 16/20 | 0.55 |
| ▸ | CDK2 | P24941 | 16/20 | 0.55 |
| ▸ | CDK7 | P50613 | 12/20 | 0.55 |
| ▸ | CCNH | P51946 | 12/20 | 0.55 |
| ▸ | MNAT1 | P51948 | 8/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22076266 | 1.00 | CCNK (0.55) | CCNKCDK12CCNT1CDK9CCNE1 | |
| SCHEMBL22076267 | 1.00 | CCNK (0.55) | CCNKCDK12CCNT1CDK9CCNE1 | |
| SCHEMBL22076295 | 0.90 | CDK7 (0.70) | CCNKCDK12CCNT1CDK9CCNE1 | |
| SCHEMBL22076293 | 0.90 | CDK7 (0.70) | CCNKCDK12CCNT1CDK9CCNE1 | |
| SCHEMBL29583380 | 0.90 | CDK7 (0.70) | CCNKCDK12CCNT1CDK9CCNE1 | |
| SCHEMBL21178413 | 0.84 | CDK7 (0.66) | CCNKCDK12CCNT1CDK9CCNE1 | |
| SCHEMBL24308297 | 0.79 | CCNK (0.68) | CCNKCDK12CCNT1CDK9CCNE1 | |
| SCHEMBL29498422 | 0.78 | CCNK (0.54) | CCNKCDK12CCNT1CDK9CCNE1 | |
| SCHEMBL22076296 | 0.77 | CCNK (0.79) | CCNKCDK12CCNT1CDK9CCNE1 | |
| SCHEMBL22076294 | 0.77 | CCNK (0.79) | CCNKCDK12CCNT1CDK9CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260035393-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 (CDK7) | SYROS PHARMACEUTICALS INC (US) | 2026-02-05 | — | — | US | disclosed |
| EP-4229038-A1 | DOSING REGIMENS FOR CYCLIN-DEPENDENT KINASE 7 (CDK7) INHIBITORS | Syros Pharmaceuticals, Inc. (US) | 2023-08-23 | — | — | EP | disclosed |
| WO-2022082056-A1 | DOSING REGIMENS FOR CYCLIN‑DEPENDENT KINASE 7 (CDK7) INHIBITORS | SYROS PHARMACEUTICALS, INC. (US) | 2022-04-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260035393-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 (CDK7) | CDK7, CDK3, CCNI | CCNK 6/4885CDK12 29/4885CCNT1 28/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.