SCHEMBL29584782

SCHEMBL29584782

Cc1cc(-c2cc(C(=O)N3[C@@H]4CC[C@H]3CC(C(=O)OCc3ccccc3)C4)n[nH]2)c(F)cn1

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ CYP4F2 P78329 1/20 0.39
▸ CYP4A11 Q02928 1/20 0.39
▸ STS P08842 1/20 0.36
▸ PIK3CA P42336 2/20 0.35
▸ MTOR P42345 2/20 0.35
▸ SLC6A3 Q01959 2/20 0.34
▸ NAMPT P43490 1/20 0.34
▸ TSHR P16473 1/20 0.34
▸ HPGD P15428 1/20 0.33
▸ KDM5A P29375 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30630511 1.00 CYP4F2 (0.39) CYP4F2CYP4A11STSPIK3CAMTOR
SCHEMBL24424190 1.00 CYP4F2 (0.39) CYP4F2CYP4A11STSPIK3CAMTOR
SCHEMBL30630698 0.91 CYP4F2 (0.36) CYP4F2CYP4A11STSPIK3CAMTOR
SCHEMBL25090842 0.91 CYP4F2 (0.36) CYP4F2CYP4A11STSPIK3CAMTOR
SCHEMBL29585274 0.91 CYP4F2 (0.36) CYP4F2CYP4A11STSPIK3CAMTOR
SCHEMBL29243764 0.84 CYP4F2 (0.38) CYP4F2CYP4A11KDM5A
SCHEMBL24424213 0.84 CYP4F2 (0.38) CYP4F2CYP4A11KDM5A
SCHEMBL30298765 0.84 CYP4F2 (0.38) CYP4F2CYP4A11KDM5A
SCHEMBL29584356 0.84 CYP4F2 (0.38) CYP4F2CYP4A11KDM5A
SCHEMBL24423931 0.84 CYP4F2 (0.38) CYP4F2CYP4A11STSPIK3CAMTOR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12606541-B2 PPARg modulators and methods of use EISAI R&D MANAGEMENT CO., LTD. (JP) 2026-04-21 — — US disclosed
EP-4240736-A1 PPAR GAMMA MODULATORS AND METHODS OF USE Eisai R&D Management Co., Ltd. (JP) 2023-09-13 — — EP disclosed
US-20230062861-A1 PPARg MODULATORS AND METHODS OF USE EISAI R&D MANAGEMENT CO., LTD. (JP) 2023-03-02 — — US disclosed
WO-2022099144-A1 ΡΡΑRγ MODULATORS AND METHODS OF USE Eisai R&D Mangement Co., Ltd. (JP) 2022-05-12 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230062861-A1 PPARg MODULATORS AND METHODS OF USE PPARG, PPARA, PPARD CYP4F2 290/4885CYP4A11 75/4885STS 2646/4885
US-12606541-B2 PPARg modulators and methods of use PPARG, PPARA, PPARD CYP4F2 523/4885CYP4A11 88/4885STS 1962/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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