Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM5A | P29375 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29243565 | 1.00 | SMO (0.38) | SMOKMT2AALDH1A1KDM5AGAA | |
| SCHEMBL29584093 | 0.89 | MEN1 (0.40) | SMOKMT2AALDH1A1KDM5AGAA | |
| SCHEMBL29583151 | 0.89 | EPHX2 (0.39) | SMOKMT2AKDM5AGAAMAPK1 | |
| SCHEMBL24424599 | 0.89 | MEN1 (0.40) | SMOKMT2AALDH1A1KDM5AGAA | |
| SCHEMBL30630648 | 0.89 | TSHR (0.39) | SMOKMT2AALDH1A1KDM5AGAA | |
| SCHEMBL24423857 | 0.89 | EPHX2 (0.39) | SMOKMT2AKDM5AGAAMAPK1 | |
| SCHEMBL29243429 | 0.89 | TSHR (0.39) | SMOKMT2AALDH1A1KDM5AGAA | |
| SCHEMBL29586158 | 0.89 | TSHR (0.39) | SMOKMT2AALDH1A1KDM5AGAA | |
| SCHEMBL29243892 | 0.89 | SMO (0.40) | SMOKMT2AALDH1A1KDM5AGAA | |
| SCHEMBL29584813 | 0.89 | MEN1 (0.40) | SMOKMT2AKDM5AGAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4240736-A1 | PPAR GAMMA MODULATORS AND METHODS OF USE | Eisai R&D Management Co., Ltd. (JP) | 2023-09-13 | — | — | EP | disclosed |
| CN-116635380-A | PPARgamma modulators and methods of use | 卫材R&D管理有限公司 | 2023-08-22 | — | — | CN | disclosed |
| WO-2022099144-A1 | ΡΡΑRγ MODULATORS AND METHODS OF USE | Eisai R&D Mangement Co., Ltd. (JP) | 2022-05-12 | — | — | WO | disclosed |