Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KDM5A | P29375 | 4/20 | 0.38 |
| ▸ | SMO | Q99835 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29243429 | 1.00 | TSHR (0.39) | TSHRKDM4EALDH1A1KDM5ASMO | |
| SCHEMBL29586158 | 1.00 | TSHR (0.39) | TSHRKDM4EALDH1A1KDM5ASMO | |
| SCHEMBL29243798 | 0.91 | MAPT (0.40) | TSHRALDH1A1KDM5ASMOGAA | |
| SCHEMBL29584822 | 0.91 | MAPT (0.40) | TSHRALDH1A1KDM5ASMOGAA | |
| SCHEMBL29584813 | 0.90 | MEN1 (0.40) | TSHRKDM5ASMOGAAUSP2 | |
| SCHEMBL29585125 | 0.90 | SMO (0.40) | TSHRALDH1A1KDM5ASMOGAA | |
| SCHEMBL29243892 | 0.90 | SMO (0.40) | TSHRALDH1A1KDM5ASMOGAA | |
| SCHEMBL29243423 | 0.90 | MEN1 (0.40) | TSHRKDM5ASMOGAAUSP2 | |
| SCHEMBL29584832 | 0.89 | SMO (0.38) | TSHRALDH1A1KDM5ASMOPOLB | |
| SCHEMBL29243565 | 0.89 | SMO (0.38) | TSHRALDH1A1KDM5ASMOPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116635380-A | PPARgamma modulators and methods of use | 卫材R&D管理有限公司 | 2023-08-22 | — | — | CN | disclosed |