Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | KDM5A | P29375 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29243756 | 1.00 | KMT2A (0.50) | KMT2AMEN1POLBMAPTACHE | |
| SCHEMBL24422946 | 0.93 | KMT2A (0.49) | KMT2AMEN1POLBMAPTACHE | |
| SCHEMBL29584116 | 0.93 | KMT2A (0.49) | KMT2AMEN1POLBMAPTACHE | |
| SCHEMBL29583230 | 0.92 | KMT2A (0.47) | KMT2AMEN1POLBMAPTACHE | |
| SCHEMBL24424310 | 0.92 | KMT2A (0.47) | KMT2AMEN1POLBMAPTACHE | |
| SCHEMBL24424347 | 0.86 | THRB (0.45) | KMT2AMEN1MAPTACHEBACE1 | |
| SCHEMBL29584425 | 0.86 | THRB (0.45) | KMT2AMEN1MAPTACHEBACE1 | |
| SCHEMBL24423922 | 0.85 | KMT2A (0.51) | KMT2AMEN1POLBMAPTALDH1A1 | |
| SCHEMBL29583326 | 0.85 | KMT2A (0.51) | KMT2AMEN1POLBMAPTALDH1A1 | |
| SCHEMBL24423689 | 0.84 | KMT2A (0.50) | KMT2AMEN1POLBMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4240736-A1 | PPAR GAMMA MODULATORS AND METHODS OF USE | Eisai R&D Management Co., Ltd. (JP) | 2023-09-13 | — | — | EP | disclosed |
| WO-2022099144-A1 | ΡΡΑRγ MODULATORS AND METHODS OF USE | Eisai R&D Mangement Co., Ltd. (JP) | 2022-05-12 | — | — | WO | disclosed |