Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25090954 | 0.90 | TLR8 (0.36) | KDM5APDE4BTLR9TLR8TLR7 | |
| SCHEMBL29584646 | 0.90 | TLR8 (0.36) | KDM5APDE4BTLR9TLR8TLR7 | |
| SCHEMBL30298816 | 0.88 | KDM5A (0.31) | KDM5APDE4B | |
| SCHEMBL29584301 | 0.87 | FFAR4 (0.37) | PDE4BTLR9TLR8TLR7 | |
| SCHEMBL25090729 | 0.87 | FFAR4 (0.37) | PDE4BTLR9TLR8TLR7 | |
| SCHEMBL24424040 | 0.87 | FFAR4 (0.37) | PDE4BTLR9TLR8TLR7 | |
| SCHEMBL30630568 | 0.87 | FFAR4 (0.37) | PDE4BTLR9TLR8TLR7 | |
| SCHEMBL24424784 | 0.83 | BACE1 (0.34) | KDM5A | |
| SCHEMBL24424783 | 0.83 | BACE1 (0.34) | KDM5A | |
| SCHEMBL25090994 | 0.83 | KDM5A (0.32) | KDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4240736-A1 | PPAR GAMMA MODULATORS AND METHODS OF USE | Eisai R&D Management Co., Ltd. (JP) | 2023-09-13 | — | — | EP | disclosed |
| WO-2022099144-A1 | ΡΡΑRγ MODULATORS AND METHODS OF USE | Eisai R&D Mangement Co., Ltd. (JP) | 2022-05-12 | — | — | WO | disclosed |