Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | TBK1 | Q9UHD2 | 3/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | MC4R | P32245 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.31 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.31 |
| ▸ | CDK9 | P50750 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25090729 | 1.00 | FFAR4 (0.37) | FFAR4TBK1TLR9TLR8TLR7 | |
| SCHEMBL24424040 | 1.00 | FFAR4 (0.37) | FFAR4TBK1TLR9TLR8TLR7 | |
| SCHEMBL29584301 | 1.00 | FFAR4 (0.37) | FFAR4TBK1TLR9TLR8TLR7 | |
| SCHEMBL30298816 | 0.92 | KDM5A (0.31) | FFAR4PDE4B | |
| SCHEMBL29584811 | 0.92 | FFAR4 (0.40) | FFAR4TBK1TLR9TLR8TLR7 | |
| SCHEMBL24423491 | 0.92 | FFAR4 (0.40) | FFAR4TBK1TLR9TLR8TLR7 | |
| SCHEMBL24423493 | 0.92 | FFAR4 (0.40) | FFAR4TBK1TLR9TLR8TLR7 | |
| SCHEMBL29584337 | 0.92 | FFAR4 (0.40) | FFAR4TBK1TLR9TLR8TLR7 | |
| SCHEMBL24424096 | 0.92 | FFAR4 (0.40) | FFAR4TBK1TLR9TLR8TLR7 | |
| SCHEMBL29584553 | 0.92 | FFAR4 (0.40) | FFAR4TBK1TLR9TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116635380-A | PPARgamma modulators and methods of use | 卫材R&D管理有限公司 | 2023-08-22 | — | — | CN | disclosed |