Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.63 |
| ▸ | NPC1 | O15118 | 5/20 | 0.63 |
| ▸ | RAB9A | P51151 | 5/20 | 0.63 |
| ▸ | MEN1 | O00255 | 4/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | HPGD | P15428 | 3/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | ATM | Q13315 | 1/20 | 0.63 |
| ▸ | KLF10 | Q13118 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.53 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.50 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29585720 | 0.88 | CSNK2A1 (0.56) | HSP90AA1SMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL6473953 | 0.87 | SMN1; SMN2 (0.78) | HSP90AA1SMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL38652442 | 0.82 | NPC1 (0.76) | HSP90AA1SMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL3817844 | 0.82 | NPC1 (0.76) | HSP90AA1SMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL11069363 | 0.81 | CSNK2A1 (0.58) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL29586454 | 0.81 | NPC1 (0.68) | HSP90AA1SMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL150915 | 0.81 | NPC1 (0.68) | HSP90AA1SMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL224762 | 0.80 | NPC1 (0.88) | HSP90AA1SMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL14363213 | 0.80 | KLF10 (0.68) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL5268587 | 0.79 | SMN1; SMN2 (0.63) | HSP90AA1SMN1; SMN2NPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111825645-B | Naphtho-coumarin compound, preparation method and application of naphthocoumarin compound as photoluminescence material | 陕西师范大学 | 2022-05-13 | — | — | CN | disclosed |