KLF10

Krueppel-like factor 10 · Q13118 · KLF10 on Sugi Atlas →

4,319 patent compounds predicted against KLF10, 2,811 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
Atomoxetine (SCHEMBL34268)	1.00	2/20
Atomoxetine (SCHEMBL341802)	1.00	2/20
Atomoxetine (SCHEMBL2209541)	1.00	2/20
Atomoxetine (SCHEMBL122111)	0.97	2/20
Atomoxetine (SCHEMBL627231)	0.97	2/20
Atomoxetine (SCHEMBL649168)	0.97	2/20
Atomoxetine (SCHEMBL1560986)	0.97	2/20
Atomoxetine (SCHEMBL2206798)	0.97	2/20
Atomoxetine (SCHEMBL1648558)	0.94	2/20
Atomoxetine (SCHEMBL4082557)	0.86	2/20
Nisoxetine (SCHEMBL4083146)	0.86	2/20
Atomoxetine (SCHEMBL4730875)	0.86	2/20
Atomoxetine (SCHEMBL5011175)	0.86	2/20
SCHEMBL2615186	0.81	2/20
SCHEMBL2738780	0.79	2/20
Atomoxetine (SCHEMBL4730438)	0.78	2/20
Atomoxetine (SCHEMBL4943829)	0.78	2/20
SCHEMBL5162645	0.73	2/20
SCHEMBL5162653	0.73	2/20
Nisoxetine (SCHEMBL124289)	0.73	2/20

Clinical trials — most relevant to KLF10 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Chronic Cold Acclimation Stimulates the Browning of Subcutaneous White Adipose in Patients With Type 2 Diabetes Mellitus	PHASE4	UNKNOWN
Adding Exenatide to Insulin Therapy for Patients With Type 2 Diabetes and Non-Alcoholic Fatty Liver Disease	PHASE4	COMPLETED
Study on the Effect of Two Ways of Cycloplegia on Biological Parameters of Ciliary Muscle	PHASE4	UNKNOWN
Deciphering Effects of Thalidomide on Red Blood Cells in Transfusion Dependents Beta Thalassemia Patients	PHASE3	COMPLETED
The Use of Inhaled Corticosteroids in the Treatment of Asthma is Children in the Emergency Room	PHASE2/PHASE3	COMPLETED
Effect of Deferoxamine on Wound Healing Rate in Patients With Diabetes Foot Ulcers	PHASE2	NOT_YET_RECRUITING
Combination of Chemoradiation Therapy and Epitope Peptide Vaccine Therapy in Treating Patients With Esophageal Cancer	PHASE1	UNKNOWN
SKB410 for Injection in Solid Tumors	PHASE1	ACTIVE_NOT_RECRUITING
Treatment Duration Increment and Pharmacodynamic Study of CX-4945 in Patients With Basal Cell Carcinoma (BCC)	PHASE1	COMPLETED
Tissue Expression of Krüppel-Like Factors 4 and 7 in Bone Tumors	nan	RECRUITING
Clinical Study of Desuzumab in the Treatment of Knee Osteoarthritis	nan	RECRUITING
Investigation of the Genetic Causes of Kallmann Syndrome and Reproductive Disorders	nan	COMPLETED
Amplification of Zinc Finger Protein 217 Gene in Multiple Myeloma	nan	UNKNOWN
Transcription Factor Runx2 in Necrotic Femoral Head Tissue	nan	COMPLETED
Autophagy in Systemic Lupus Erythematosus	nan	UNKNOWN
Effect of Post Covid-19 Hypoxia on Placenta of Normal Pregnant Women: A Possible Role of Hypoxia Inducible Factor-1α.	nan	UNKNOWN
Mitochondrial Activity and Myosteatosis in the Cachexia of Cancers of the Upper Aerodigestive Tract	nan	UNKNOWN
Transcriptional and Epigenetic Program of PCOS Women	nan	ACTIVE_NOT_RECRUITING
Klotho _ LRP-6 _ Gastric Adenocarcinoma	nan	UNKNOWN
EPIgenetics and in Vivo Resistance of Chronic Myeloid Leukemia Stem Cells to Tyrosine Kinase Inhibitors	nan	UNKNOWN
TIGIT in Patients With Chronic Myeloid Leukemia	nan	UNKNOWN
EKLF Gene Expression in β-thalassemia	nan	NOT_YET_RECRUITING
Azoospermia Patients	nan	RECRUITING
A Study to See if Low Level Laser Light Therapy (LLLT) Can Improve the Condition of Nonalcoholic Steatohepatitis (NASH)	nan	WITHDRAWN
Gene Expression Variation and Implant Wound Healing Among Smokers and Diabetics	nan	COMPLETED
Circulating Biomarker Signatures for the Detection of Gastric Preneoplasia and Cancer	nan	RECRUITING
Placental and Cord Blood Markers Associated With Premature Birth and Disorders of Premature Birth in Newborn Infants	nan	COMPLETED
Comparison Of Efficacy Of Tazarotene 0.045% Vs Halobetasol Propionate 0.01% Lotion For Treatment of Scalp Psoriasis	nan	COMPLETED
Mild Intermittent Hypoxia and Its Multipronged Effect on Sleep Apnea	nan	RECRUITING
Genetical Background of Non-alcoholic Fatty Liver Disease (NAFLD) in Diabetes Mellitus and in Chronic Kidney Disease	nan	UNKNOWN

Related proteins — ESM-2 sequence neighbours (a KLF10 binder may also engage these)

Protein	Name	Similarity
O08876	—	1.000	O08876 →
P57682	—	0.997	P57682 →
Q10938	—	0.996	Q10938 →
O35738	—	0.996	O35738 →
O89091	—	0.995	O89091 →
P46200	—	0.995	P46200 →
P70284	—	0.995	P70284 →
P06537	—	0.995	P06537 →
Q3YC04	—	0.995	Q3YC04 →
P06536	—	0.994	P06536 →
Q4JM28	—	0.994	Q4JM28 →
Q8VII8	—	0.994	Q8VII8 →
Q2KHR2	—	0.994	Q2KHR2 →
A0A1L8H0H2	—	0.993	A0A1L8H0H2 →
P10244	—	0.993	P10244 →
Q64318	—	0.993	Q64318 →
O60315	—	0.993	O60315 →
A0A5E4M3Q4	—	0.993	A0A5E4M3Q4 →
Q80WT2	—	0.993	Q80WT2 →
Q6NRM0	—	0.993	Q6NRM0 →
Q90655	—	0.993	Q90655 →
P49844	—	0.993	P49844 →
A0JN51	—	0.993	A0JN51 →
Q91904	—	0.993	Q91904 →
Q29131	—	0.992	Q29131 →
Q9R0G7	—	0.992	Q9R0G7 →
Q64163	—	0.992	Q64163 →
Q499D0	—	0.992	Q499D0 →
Q9ULH7	—	0.992	Q9ULH7 →
Q9N1U3	—	0.992	Q9N1U3 →