SCHEMBL29586286

SCHEMBL29586286

O=C1CCC(Oc2cc3ccccc3s2)CC1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 3/20 0.38
HCRTR1 O43613 1/20 0.37
HCRTR2 O43614 1/20 0.37
CA12 O43570 2/20 0.37
CA9 Q16790 2/20 0.37
CA2 P00918 2/20 0.37
CA1 P00915 1/20 0.37
CA4 P22748 1/20 0.37
CA5A P35218 1/20 0.37
CA7 P43166 1/20 0.37
CA14 Q9ULX7 1/20 0.37
CA5B Q9Y2D0 1/20 0.37
BCL2L1 Q07817 1/20 0.37
PDE4A P27815 1/20 0.36
PDE4B Q07343 1/20 0.36
PDE4C Q08493 1/20 0.36
PDE4D Q08499 1/20 0.36
CHRM2 P08172 1/20 0.35
CHRM4 P08173 1/20 0.35
CHRM5 P08912 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21047609 1.00 CYP2A6 (0.38) CYP2A6HCRTR1HCRTR2CA12CA9
SCHEMBL4147085 0.76 SLC6A4 (0.52) CYP2A6CA12CA9CA2CA1
SCHEMBL21047700 0.74 PTGS1 (0.43) HCRTR1HCRTR2PTGS1PTGS2
SCHEMBL21047620 0.71 CYP2A6 (0.37) CYP2A6HCRTR1HCRTR2CA12CA9
SCHEMBL29586210 0.71 CYP2A6 (0.37) CYP2A6HCRTR1HCRTR2CA12CA9
SCHEMBL21047569 0.71 ALOX5 (0.37) CYP2A6CA12CA9CA2CA1
SCHEMBL29587505 0.71 HDAC3 (0.37) CYP2A6CA12CA9CA2CA1
SCHEMBL21047915 0.71 HDAC3 (0.37) CYP2A6CA12CA9CA2CA1
SCHEMBL21047593 0.70 PDE4A (0.36) PDE4APDE4BPDE4CPDE4D
SCHEMBL21047871 0.69 CA12 (0.41) CYP2A6CA12CA9CA2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109563016-B Method for producing perfluoroalkyl compound using monohydroperfluoroalkane as starting material 关东电化工业株式会社 2022-05-13 CN disclosed