Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21326011 | 1.00 | PDGFRB (0.58) | PDGFRBHSP90AB1 | |
| SCHEMBL17893602 | 0.93 | — | — | |
| SCHEMBL22295251 | 0.92 | HSP90AB1 (0.54) | PDGFRBHSP90AB1 | |
| SCHEMBL21325974 | 0.92 | HSP90AB1 (0.68) | PDGFRBHSP90AB1 | |
| SCHEMBL29586646 | 0.92 | HSP90AB1 (0.68) | HSP90AB1 | |
| SCHEMBL21326025 | 0.92 | HSP90AB1 (0.68) | HSP90AB1 | |
| SCHEMBL29587216 | 0.92 | HSP90AB1 (0.68) | PDGFRBHSP90AB1 | |
| SCHEMBL29586968 | 0.90 | — | — | |
| SCHEMBL21325983 | 0.90 | GRM5 (0.54) | PDGFRBHSP90AB1 | |
| SCHEMBL21326001 | 0.90 | PDGFRB (0.60) | PDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110088103-B | Novel tetrahydropyridopyrimidine compounds for the treatment and prophylaxis of hepatitis b virus infection | 豪夫迈·罗氏有限公司 | 2022-04-12 | — | — | CN | claimed |
| CN-110088103-B | Novel tetrahydropyridopyrimidine compounds for the treatment and prophylaxis of hepatitis b virus infection | 豪夫迈·罗氏有限公司 | 2022-04-12 | — | — | CN | disclosed |