Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Farnesyl Diphosphate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 13/20 | 0.61 |
| ▸ | FNTB | P49356 | 11/20 | 0.61 |
| ▸ | PGGT1B | P53609 | 4/20 | 0.61 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Geranyl Diphosphate SCHEMBL30981527 | 0.98 | FNTA (0.58) | FNTAFNTBPGGT1BGGPS1 | |
| SCHEMBL20839374 | 0.97 | FNTA (0.61) | FNTAFNTBPGGT1BGGPS1 | |
| SCHEMBL451534 | 0.97 | FNTA (0.61) | FNTAFNTBPGGT1BGGPS1 | |
| Geranyl Diphosphate SCHEMBL27582115 | 0.95 | FNTA (0.58) | FNTAFNTBPGGT1BGGPS1 | |
| Geranyl Diphosphate SCHEMBL152950 | 0.95 | FNTA (0.58) | FNTAFNTBPGGT1BGGPS1 | |
| SCHEMBL451532 | 0.87 | FNTA (0.72) | FNTAFNTBPGGT1B | |
| Farnesyl Diphosphate SCHEMBL153997 | 0.87 | FNTA (0.72) | FNTAFNTBPGGT1B | |
| Geranyl Diphosphate SCHEMBL30981622 | 0.85 | FNTA (0.48) | FNTAFNTBPGGT1BGGPS1 | |
| SCHEMBL18042460 | 0.80 | FNTA (0.69) | FNTAFNTBPGGT1B | |
| SCHEMBL1978483 | 0.80 | FNTA (0.69) | FNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220162188-A1 | ISOPRENOIDS AND METHODS OF MAKING THEREOF | NORTH CAROLINA STATE UNIVERSITY | 2022-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220162188-A1 | ISOPRENOIDS AND METHODS OF MAKING THEREOF | GGPS1, SQLE, FDPS | FNTA 14/4885FNTB 31/4885PGGT1B 261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.