Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 8/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 8/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 4/20 | 0.38 |
| ▸ | PPARA | Q07869 | 3/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD5 | P21918 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29587197 | 0.86 | PPARG (0.43) | CYP4F2CYP4A11MEN1KMT2APPARG | |
| SCHEMBL29586811 | 0.83 | MAOB (0.43) | CYP4F2CYP4A11MEN1KMT2APPARG | |
| SCHEMBL24496643 | 0.83 | CYP4F2 (0.51) | CYP4F2CYP4A11PPARGPPARAHDAC3 | |
| SCHEMBL29587347 | 0.83 | CYP4F2 (0.51) | CYP4F2CYP4A11PPARGPPARAHDAC3 | |
| SCHEMBL24496752 | 0.83 | EGLN1 (0.39) | CYP4F2CYP4A11MEN1KMT2APPARG | |
| SCHEMBL29586879 | 0.83 | EGLN1 (0.39) | CYP4F2CYP4A11MEN1KMT2APPARG | |
| SCHEMBL29587290 | 0.82 | HDAC3 (0.51) | CYP4F2CYP4A11HDAC3HDAC1HDAC2 | |
| SCHEMBL24496642 | 0.80 | CYP4F2 (0.51) | CYP4F2CYP4A11PPARGPPARAHDAC3 | |
| SCHEMBL29587210 | 0.80 | PPARG (0.46) | CYP4F2CYP4A11MEN1KMT2APPARG | |
| SCHEMBL24496639 | 0.76 | CYP4F2 (0.48) | CYP4F2CYP4A11MEN1KMT2APPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022120048-A1 | HDAC INHIBITORS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2022-06-09 | — | — | WO | disclosed |