Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21326102 | 1.00 | HTR2A (0.31) | HTR2AHTR2CHTR2BMAOB | |
| SCHEMBL29507238 | 0.82 | HTR2C (0.36) | HTR2AHTR2CHTR2B | |
| SCHEMBL21326101 | 0.82 | SLC6A4 (0.36) | HTR2AHTR2CHTR2B | |
| SCHEMBL22858964 | 0.82 | HTR2C (0.36) | HTR2AHTR2CHTR2B | |
| SCHEMBL29586528 | 0.82 | SLC6A4 (0.36) | HTR2AHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL31597892 | 0.81 | HTR2C (0.35) | HTR2AHTR2CHTR2B | |
| SCHEMBL21339876 | 0.78 | — | — | |
| SCHEMBL38655284 | 0.76 | — | — | |
| SCHEMBL21326037 | 0.76 | MAOA (0.36) | — | |
| SCHEMBL29586596 | 0.76 | MAOA (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115297861-B | Compounds and uses thereof | 福宏治疗公司 | 2024-07-12 | — | — | CN | disclosed |
| CN-115297861-A | Compound and use thereof | 福宏治疗公司 | 2022-11-04 | — | — | CN | disclosed |
| CN-109863145-B | Novel tetrahydroisoquinoline and tetrahydronaphthyridine compounds for the treatment and prevention of hepatitis b virus infection | 豪夫迈·罗氏有限公司 | 2022-04-12 | — | — | CN | disclosed |